Evidence map›Paper›PMID 21985340›Full record

ArticleCough (London, England)2011

Cough management: a practical approach.

Francesco De Blasio, Johann C Virchow, Mario Polverino, Alessandro Zanasi, Panagiotis K Behrakis, Gunsely Kilinç, Rossella Balsamo, Gianluca De Danieli, Luigi Lanata

Open access · hybridAbstract read
In one paragraph

Article in Cough (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 105 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Coughing in Small Animal Patients.Frontiers in veterinary science · 2019
    Review
  10. Article
  11. Article
  12. Productive Cough in Children and Adolescents - View from Primary Health Care System.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2017
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Anatomy and neuro-pathophysiology of the cough reflex arc.Multidisciplinary respiratory medicine · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Francesco De BlasioMedical Department, Dompé S,P,A, via San Martino 12, Milan, Italy. gianluca.dedanieli@dompe.it.
Johann C Virchow
Mario Polverino
Alessandro Zanasi
Panagiotis K Behrakis
Gunsely Kilinç
Rossella Balsamo
Gianluca De Danieli
Luigi Lanata
Dompé (Italy) · ITASL Roma · ITIstanbul University · TRNational and Kapodistrian University of Athens · GRPoliclinico S.Orsola-Malpighi · ITUniversity of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cough is one of the most common symptoms for which patients seek medical attention from primary care physicians and pulmonologists. Cough is an important defensive reflex that enhances the clearance of secretions and particles from the airways and protects the lower airways from the aspiration of foreign materials. Therapeutic suppression of cough may be either disease-specific or symptom related. The potential benefits of an early treatment of cough could include the prevention of the vicious cycle of cough. There has been a long tradition in acute cough, which is frequently due to upper respiratory tract infections, to use symptom-related anti-tussives. Suppression of cough (during chronic cough) may be achieved by disease-specific therapies, but in many patients it is often necessary to use symptomatic anti-tussives, too. According to the current guidelines of the American College of Chest Physician on "Cough Suppressants and Pharmacologic Protussive Therapy" and additional clinical trials on the most frequent anti-tussive drugs, it should be possible to diagnose and treat cough successfully in a majority of cases. Among drugs used for the symptomatic treatment of cough, peripherally acting anti-tussives such as levodropropizine and moguisteine show the highest level of benefit and should be recommended especially in children. By improving our understanding of the specific effects of these anti-tussive agents, the therapeutic use of these drugs may be refined. The present review provides a summary of the most clinically relevant anti-tussive drugs in addition to their potential mechanism of action.

Identifiers

PMID21985340
PMCPMC3205006
OpenAlexW2131101604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.