ReviewDevelopmental cognitive neuroscience2011
Oxytocin and social motivation.
Review in Developmental cognitive neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
73 citing papers in PubMed.
- Oxytocin Enhances an Amygdala Circuit Associated With Negative Symptoms in Schizophrenia: A Single-Dose, Placebo-Controlled, Crossover, Randomized Control Trial.Schizophrenia bulletin · 2020Trial
- Oxytocin Receptor Gene Variant Interacts with Intervention Delivery Format in Predicting Intervention Outcomes for Youth with Conduct Problems.Prevention science : the official journal of the Society for Prevention Research · 2018Trial
- Electrophysiological correlates of oxytocin-induced enhancement of social performance monitoring.Social cognitive and affective neuroscience · 2017Trial
- Oxytocin modulates hemodynamic responses to monetary incentives in humans.Psychopharmacology · 2016Trial
- Intranasal Oxytocin Enhances Connectivity in the Neural Circuitry Supporting Social Motivation and Social Perception in Children with Autism.Scientific reports · 2016Trial
- The effects of intranasal oxytocin in opioid-dependent individuals and healthy control subjects: a pilot study.Psychopharmacology · 2016Trial
- Oxytocin increases VTA activation to infant and sexual stimuli in nulliparous and postpartum women.Hormones and behavior · 2015Trial
- Oxytocin and cortisol in goat milk during early lactation under different housing conditions: a descriptive study.Frontiers in veterinary science · 2026Article
- Autonomic nervous system dysfunction in irritable bowel syndrome: pathophysiology and therapeutic implications.Frontiers in neuroscience · 2026Review
- Three-dimensional quantification of oxytocin neurons in the hypothalamic paraventricular nucleus reveals sex- and subregion-specific differences in two genetic mouse models of autism.Journal of neuroendocrinology · 2025Article
- Oxytocin administration to clinicians in acute psychiatric care settings: a feasibility study.Frontiers in psychiatry · 2025Article
- How Do Common Marmosets Maintain the Balance Between Response Execution and Action Inhibition?American journal of primatology · 2025Article
- Article
- Murine vaginal secretory responses to a male volatile chemical messenger.Scientific reports · 2024Article
- Oxytocin influences parental care in male threespine stickleback across multiple time scales.Hormones and behavior · 2024Article
- Epigenetic modification of the oxytocin receptor gene is associated with child-parent neural synchrony during competition.Developmental cognitive neuroscience · 2023Article
- Social Psychopharmacology: Novel Approaches to Treat Deficits in Social Motivation in Schizophrenia.Schizophrenia bulletin · 2023Review
- Sniffing oxytocin: Nose to brain or nose to blood?Molecular psychiatry · 2023Article
- Oxytocin receptor antagonism during early vocal learning reduces song preference and imitation in zebra finches.Scientific reports · 2023Article
- From Oxytocin to Compassion: The Saliency of Distress.Biology · 2023Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Humans are fundamentally social creatures who are ‘motivated’ to be with others. In this review we examine the role of oxytocin (OT) as it relates to social motivation. OT is synthesized in the brain and throughout the body, including in the heart, thymus, gastrointestinal tract, as well as reproductive organs. The distribution of the OT receptor (OTR) system in both the brain and periphery is even more far-reaching and its expression is subject to changes over the course of development. OTR expression is also sensitive to changes in the external environment and the internal somatic world. The OT system functions as an important element within a complex, developmentally sensitive biobehavioral system. Other elements include sensory inputs, the salience, reward, and threat detection pathways, the hypothalamic-pituitary-gonadal axis, and the hypothalamic-pituitary-adrenal stress response axis. Despite an ever expanding scientific literature, key unresolved questions remain concerning the interplay of the central and peripheral components of this complex biobehavioral system that dynamically engages the brain and the body as humans interact with social partners over the course of development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.