ArticleCognitive processing2012
Toward operational architectonics of consciousness: basic evidence from patients with severe cerebral injuries.
Article in Cognitive processing, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Patients with Disorders of Consciousness: Are They Nonconscious, Unconscious, or Subconscious? Expanding the Discussion.Brain sciences · 2023Article
- A guideline for linking brain wave findings to the various aspects of discrete perception.The European journal of neuroscience · 2022Review
- Placing pure experience of Eastern tradition into the neurophysiology of Western tradition.Cognitive neurodynamics · 2019Article
- Measuring the Complexity of Consciousness.Frontiers in neuroscience · 2018Article
- Large-Scale Brain Simulation and Disorders of Consciousness. Mapping Technical and Conceptual Issues.Frontiers in psychology · 2018Article
- Network Properties in Transitions of Consciousness during Propofol-induced Sedation.Scientific reports · 2017Article
- The Chief Role of Frontal Operational Module of the Brain Default Mode Network in the Potential Recovery of Consciousness from the Vegetative State: A Preliminary Comparison of Three Case Reports.The open neuroimaging journal · 2016Article
- Long-Term (Six Years) Clinical Outcome Discrimination of Patients in the Vegetative State Could be Achieved Based on the Operational Architectonics EEG Analysis: A Pilot Feasibility Study.The open neuroimaging journal · 2016Article
- Spherical Harmonics Reveal Standing EEG Waves and Long-Range Neural Synchronization during Non-REM Sleep.Frontiers in computational neuroscience · 2016Article
- Intrathecal baclofen: effects on spasticity, pain, and consciousness in disorders of consciousness and locked-in syndrome.Current pain and headache reports · 2015Review
- Autonomic correlates of seeing one's own face in patients with disorders of consciousness.Neuroscience of consciousness · 2015Article
- Assessing learning as a possible sign of consciousness in post-coma persons with minimal responsiveness.Frontiers in human neuroscience · 2014Article
- Do we need a theory-based assessment of consciousness in the field of disorders of consciousness?Frontiers in human neuroscience · 2014Article
- The perception of pain and its management in disorders of consciousness.Current pain and headache reports · 2013Review
- Subgraph "backbone" analysis of dynamic brain networks during consciousness and anesthesia.PloS one · 2013Article
- DMN Operational Synchrony Relates to Self-Consciousness: Evidence from Patients in Vegetative and Minimally Conscious States.The open neuroimaging journal · 2012Article
- Long-lasting coma.Functional neurologyArticle
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Although several studies propose that the integrity of neuronal assemblies may underlie a phenomenon referred to as awareness, none of the known studies have explicitly investigated dynamics and functional interactions among neuronal assemblies as a function of consciousness expression. In order to address this question, EEG operational architectonics analysis (Fingelkurts and Fingelkurts 2001, 2008) was conducted in patients in minimally conscious (MCS) and vegetative states (VS) to study the dynamics of neuronal assemblies and operational synchrony among them as a function of consciousness expression. We found that in minimally conscious patients and especially in vegetative patients neuronal assemblies got smaller, their life span shortened and they became highly unstable. Furthermore, we demonstrated that the extent/volume and strength of operational synchrony among neuronal assemblies was smallest or even absent in VS patients, intermediate in MCS patients, and highest in healthy fully conscious subjects. All findings were similarly observed in EEG alpha as well as beta1 and beta2 frequency oscillations. The presented results support the basic tenets of operational architectonics theory of brain-mind functioning and suggest that EEG operational architectonics analysis may provide an objective and accurate means of assessing signs of (un)consciousness in patients with severe brain injuries. Therefore, this methodological approach may complement the existing "gold standard" of behavioral assessment of this population of challenging patients and inform the diagnostic and treatment decision-making processes.
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