SynthesisCancer causes & control : CCC2012
Vitamin D and mammographic breast density: a systematic review.
Synthesis in Cancer causes & control : CCC, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Chemoprevention Agents to Reduce Mammographic Breast Density in Premenopausal Women: A Systematic Review of Clinical Trials.JNCI cancer spectrum · 2021Pooled it
- Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised trials.BMJ (Clinical research ed.) · 2014Pooled it
- Randomized Double-Blind Placebo-Controlled Biomarker Modulation Study of Vitamin D Supplementation in Premenopausal Women at High Risk for Breast Cancer (SWOG S0812).Cancer prevention research (Philadelphia, Pa.) · 2019Trial
- Statistically Significant Association Does not Imply Improvement in Prediction of Clinical Outcomes.Cancer prevention research (Philadelphia, Pa.) · 2025Article
- Multivitamin Use and Mammographic Breast Density.The Journal of nutrition · 2025Article
- The association of metformin and aspirin intake with mammographic breast density: A cross-sectional study.Caspian journal of internal medicine · 2023Article
- Association Between Lifestyle Changes, Mammographic Breast Density, and Breast Cancer.The oncologist · 2022Review
- Air pollution exposure and mammographic breast density in Tehran, Iran: a cross-sectional study.Environmental health and preventive medicine · 2022Article
- Association between skeletal muscle mass and mammographic breast density.Scientific reports · 2021Article
- Adjuvant Therapy and Mammographic Density Changes in Women With Breast Cancer.JNCI cancer spectrum · 2018Article
- Article
- Increased vitamin D and calcium intake associated with reduced mammographic breast density among premenopausal women.Nutrition research (New York, N.Y.) · 2015Article
- Safety, Feasibility, and Biomarker Effects of High-Dose Vitamin D Supplementation Among Women at High Risk for Breast Cancer.International journal of food science, nutrition and dietetics · 2015Article
- Premenopausal plasma 25-hydroxyvitamin D, mammographic density, and risk of breast cancer.Breast cancer research and treatment · 2015Article
- Mammographic density and serum 25-hydroxyvitamin D levels.Nutrition & metabolism · 2014Article
- Vitamin d: are we ready to supplement for breast cancer prevention and treatment?ISRN oncology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Studies suggest a protective relationship between Vitamin D and breast cancer risk. Several studies assessed the association of Vitamin D with mammographic breast density, a known and strong breast cancer risk factor. Understanding the potential role of Vitamin D in the modification of breast density might open new avenues in breast cancer prevention. This systematic review summarizes published studies that investigated the association between Vitamin D and mammographic breast density and offers suggestions for strategies to advance our scientific knowledge.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.