Evidence map›Paper›PMID 21982702›Full record

ArticleCell metabolism2011

DisseCCTing phospholipid function in lipid droplet dynamics.

Dawn L Brasaemle

Abstract readComment
In one paragraph

Article in Cell metabolism, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Dawn L BrasaemleRutgers Center for Lipid Research, Rutgers University, New Brunswick, NJ 08901, USA. brasaemle@aesop.rutgers.edu

Funding

PERILIPINS AND CELLULAR TRIACYLGLYCEROL METABOLISMR01DK054797 · NIDDK · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI BRASAEMLE, DAWN L · 2000 to 2014
$3.9M
NIDDK NIH HHS R01 DK054797
6 · The paper itself

Abstract

Phospholipids provide an amphipathic barrier between lipid droplets and the cytoplasm of cells. In this issue of Cell Metabolism, Krahmer and colleagues (2011) define a role for phosphatidylcholine in preventing lipid droplet coalescence and show that the rate-limiting enzyme in phosphatidylcholine synthesis is activated through binding to lipid droplets.

Identifiers

PMID21982702
PMCPMC3211137

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.