ArticleJournal of bacteriology1990
Thermotolerance is independent of induction of the full spectrum of heat shock proteins and of cell cycle blockage in the yeast Saccharomyces cerevisiae.
Article in Journal of bacteriology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 50 citations in OpenAlex.
- Dynamic global acetylation remodeling during the yeast heat shock response.Genome biology · 2026Article
- Examining the condition-specific antisense transcription in S. cerevisiae and S. paradoxus.BMC genomics · 2014Article
- Biology of the heat shock response and protein chaperones: budding yeast (Saccharomyces cerevisiae) as a model system.Microbiology and molecular biology reviews : MMBR · 2012Review
- Biotechnological properties of distillery and laboratory yeasts in response to industrial stresses.Journal of industrial microbiology & biotechnology · 2010Article
- Slow growth induces heat-shock resistance in normal and respiratory-deficient yeast.Molecular biology of the cell · 2009Article
- Stress-activated genomic expression changes serve a preparative role for impending stress in yeast.Molecular biology of the cell · 2008Article
- Cytotoxic and genotoxic consequences of heat stress are dependent on the presence of oxygen in Saccharomyces cerevisiae.Journal of bacteriology · 2001Article
- Proteasome inhibitors cause induction of heat shock proteins and trehalose, which together confer thermotolerance in Saccharomyces cerevisiae.Molecular and cellular biology · 1998Article
- Synergy between trehalose and Hsp104 for thermotolerance in Saccharomyces cerevisiae.Genetics · 1996Article
- Acquired thermotolerance and heat shock proteins in thermophiles from the three phylogenetic domains.Journal of bacteriology · 1994Article
- Methionine-mediated lethality in yeast cells at elevated temperature.Journal of bacteriology · 1993Article
- Stress response of yeast.The Biochemical journal · 1993Review
- Heat shock-mediated cell cycle blockage and G1 cyclin expression in the yeast Saccharomyces cerevisiae.Molecular and cellular biology · 1993Article
- Characterization of the heat shock response in Enterococcus faecalis.Antonie van Leeuwenhoek · 1993Article
- Thermotolerance of heat-shocked Listeria monocytogenes in milk exposed to high-temperature, short-time pasteurization.Applied and environmental microbiology · 1992Article
- Hsp104 is required for tolerance to many forms of stress.The EMBO journal · 1992Article
- Uncoupling thermotolerance from the induction of heat shock proteins.Proceedings of the National Academy of Sciences of the United States of America · 1991Article
- Trehalose synthesis genes are controlled by the putative sigma factor encoded by rpoS and are involved in stationary-phase thermotolerance in Escherichia coli.Journal of bacteriology · 1991Article
- Prolonged environmental stress via a two step process selects mutants of Escherichia, Salmonella and Pseudomonas that grow at 54 degrees C.Archives of microbiology · 1991Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cells of the yeast Saccharomyces cerevisiae are known to acquire thermotolerance in response to the stresses of starvation or heat shock. We show here through the use of cell cycle inhibitors that blockage of yeast cells in the G1, S, or G2 phases of the mitotic cell cycle is not a stress that induces thermotolerance; arrested cells remained as sensitive to thermal killing as proliferating cells. These G1- or S-phase-arrested cells were unimpaired in the acquisition of thermotolerance when subjected to a mild heat shock by incubation at 37 degrees C. One cell cycle inhibitor, o-phenanthroline, did in fact cause cells to become thermotolerant but without induction of the characteristic pattern of heat shock proteins. Thermal induction of heat shock protein synthesis was unaffected; the o-phenanthroline-treated cells could still synthesize heat shock proteins upon transfer to 37 degrees C. Use of a novel mutant conditionally defective only for the resumption of proliferation from stationary phase (M. A. Drebot, G. C. Johnston, and R. A. Singer, Proc. Natl. Acad. Sci. USA 84:7948-7952, 1987) indicated that o-phenanthroline inhibition produces a stationary-phase arrest, a finding which is consistent with the increased thermotolerance and regulated cessation of proliferation exhibited by the inhibited cells. These findings show that the acquired thermotolerance of cells is unrelated to blockage of the mitotic cell cycle or to the rapid synthesis of the characteristic spectrum of heat shock proteins.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.