ArticlePediatric clinics of North America2011
Pediatric disorders of water balance.
Article in Pediatric clinics of North America, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Distribution of plasma copeptin levels and influence of obesity in children and adolescents.European journal of pediatrics · 2021Article
- Case report: severe asymptomatic hyponatremia in Prader-Willi Syndrome.BMC pediatrics · 2016Article
- High-salt diets during pregnancy affected fetal and offspring renal renin-angiotensin system.The Journal of endocrinology · 2013Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Fluid homeostasis requires adequate water intake, regulated by an intact thirst mechanism and appropriate free water excretion by the kidneys, mediated by appropriate secretion of arginine vasopressin (AVP, also known as antidiuretic hormone). AVP exerts its antidiuretic action by binding to the X chromosome-encoded V2 vasopressin receptor (V2R), a G protein coupled receptor on the basolateral membrane of renal collecting duct epithelial cells. After V2R activation, increased intracellular cyclic adenosine monophosphate mediates shuttling of the water channel aquaporin 2 to the apical membrane of collecting duct cells, resulting in increased water permeability and antidiuresis. Clinical disorders of water balance are common, and abnormalities in many steps involving AVP secretion and responsiveness have been described. This article focuses on the principal disorders of water balance, diabetes insipidus, and the syndrome of inappropriate antidiuretic hormone secretion.
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