Evidence map›Paper›PMID 21981681›Full record

ArticleAddiction (Abingdon, England)2012

Is alcohol dependence best viewed as a chronic relapsing disorder?

John A Cunningham, Jim McCambridge

Open access · bronzeAbstract read
In one paragraph

Article in Addiction (Abingdon, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. A meta-review of the evidence on addiction recovery mutual help organizations.Alcohol and alcoholism (Oxford, Oxfordshire) · 2026
    Review
  5. Article
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  13. Producing co-production: Reflections on the development of a complex intervention.Health expectations : an international journal of public participation in health care and health policy · 2020
    Article
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

John A CunninghamCentre for Addiction and Mental Health, Toronto, Ontario, Canada.
Jim McCambridge
Centre for Addiction and Mental Health · CALondon School of Hygiene & Tropical Medicine · GB

Funding

Wellcome TrustWellcome Trust WT086516MA
6 · The paper itself

Abstract

This 'For Debate' paper starts by recognizing the growing trend towards considering alcohol dependence as a chronic relapsing disorder. We argue that the adoption of this model results from focusing on those in treatment for alcohol dependence rather than considering the larger number of people in the general population who meet criteria for alcohol dependence at some point in their lives. The majority of the general population who ever experience alcohol dependence do not behave as though they have a chronic relapsing disorder: they do not seek treatment, resolve their dependence themselves and do not relapse repeatedly. We suggest that caution is therefore needed in using the chronic relapsing disorder label. Our primary concerns are that this formulation privileges biological aspects of dependence to the detriment of psychological and social contributions, it inhibits much-needed developments in understanding alcohol dependence and leads to inefficient distributions of public health and clinical care resources for alcohol dependence. We invite debate on this issue.

Indexed as

Public HealthAlcoholismBehavior, AddictiveChronic DiseaseDiagnostic and Statistical Manual of Mental DisordersHumansMiddle AgedPatient Acceptance of Health CareRecurrenceSeverity of Illness IndexYoung Adult

Identifiers

PMID21981681
PMCPMC3272223
OpenAlexW2100850717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.