ArticleACS nano2011
Computational investigation of DNA detection using graphene nanopores.
Article in ACS nano, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed.
- Addressing the Challenges of Solid-State Nanopores: Strategies for Performance Enhancement.International journal of molecular sciences · 2026Review
- Exploring 2D Graphene-Based Nanomaterials for Biomedical Applications: A Theoretical Modeling Perspective.Small science · 2025Article
- Graphene Nanopore Fabrication and Applications.International journal of molecular sciences · 2025Review
- Effect of surface functionalization on DNA sequencing using MXene-based nanopores.RSC advances · 2024Article
- Moderate binding of villin headpiece protein to CScientific reports · 2023Article
- Adsorption of DNA nucleobases on single-layer TiAIP advances · 2023Article
- Instability and translocation through nanopores of DNA interacting with single-layer materials.RSC advances · 2020Article
- Exploring the pore charge dependence of KRSC advances · 2019Article
- DNA Translocation through Hybrid Bilayer Nanopores.The journal of physical chemistry. C, Nanomaterials and interfaces · 2019Article
- An Overview of Molecular Modeling for Drug Discovery with Specific Illustrative Examples of Applications.Molecules (Basel, Switzerland) · 2019Review
- A potential sensing mechanism for DNA nucleobases by optical properties of GO and MoSScientific reports · 2019Article
- Colloquium: Ionic phenomena in nanoscale pores through 2D materials.Reviews of modern physics · 2019Article
- Ion transport through a nanoporous CRSC advances · 2018Article
- Graphene and Graphene-Based Nanomaterials for DNA Detection: A Review.Molecules (Basel, Switzerland) · 2018Review
- Golden aspect ratio for ion transport simulation in nanopores.Physical review. E · 2018Article
- Conic shapes have higher sensitivity than cylindrical ones in nanopore DNA sequencing.Scientific reports · 2018Article
- Solid-State Nanopore.Nanoscale research letters · 2018Review
- Maxwell-Hall access resistance in graphene nanopores.Physical chemistry chemical physics : PCCP · 2018Article
- Interfacing Graphene-Based Materials With Neural Cells.Frontiers in systems neuroscience · 2018Review
- Detection of methylation on dsDNA using nanopores in a MoSNanoscale · 2017Article
Corrections and comments
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Authors and funding
4 authors.
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Abstract
Nanopore-based single-molecule detection and analysis have been pursued intensively over the past decade. One of the most promising applications in this regard is DNA sequencing achieved through DNA translocation-induced blockades in ionic current. Recently, nanopores fabricated in graphene sheets were used to detect double-stranded DNA. Due to its subnanometer thickness, graphene nanopores show great potential to realize DNA sequencing at single-base resolution. Resolving at the atomic level electric field-driven DNA translocation through graphene nanopores is crucial to guide the design of graphene-based sequencing devices. Molecular dynamics simulations, in principle, can achieve such resolution and are employed here to investigate the effects of applied voltage, DNA conformation, and sequence as well as pore charge on the translocation characteristics of DNA. We demonstrate that such simulations yield current characteristics consistent with recent measurements and suggest that under suitable bias conditions A-T and G-C base pairs can be discriminated using graphene nanopores.
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