Evidence map›Paper›PMID 21979988›Full record

ArticleEuropean heart journal2012

Mitohormesis: another pleiotropic effect of statins?

James K Liao

Abstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in European heart journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

James K Liao

Funding

Tissue AnalysesP01HL048743 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI GLADYSHEV, VADIM N. · 1992 to 2014
$26.3M
LIPOPROTEINS EFFECTS ON G PROTEIN FUNCTIONR01HL052233 · NHLBI · UNIVERSITY OF CHICAGO · PI LIAO, JAMES KUANG-JAN · 1995 to 2016
$5.3M
Activation of eNOS by Steroid HormonesR01HL070274 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LIAO, JAMES KUANG-JAN · 2002 to 2006
$2.2M
Role of PI3-Kinase in Estrogen-induced eNOS ActivationR01DK062729 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI LIAO, JAMES KUANG-JAN · 2003 to 2007
$1.9M
Novel Signaling Pathways in Ischemic StrokeR01NS070001 · NINDS · UNIVERSITY OF CHICAGO · PI LIAO, JAMES KUANG-JAN · 2010 to 2014
$1.8M
ROCK and ObesityR01DK085006 · NIDDK · UNIVERSITY OF CHICAGO · PI LIAO, JAMES KUANG-JAN · 2010 to 2014
$1.7M
Endothelial Akt in Vascular InjuryR01HL080187 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LIAO, JAMES KUANG-JAN · 2006 to 2009
$1.6M
Role of protein kinase Akt in cerebral ischemiaP01NS010828 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI MOSKOWITZ, MICHAEL A. · 1989 to 2008
$1.4M
NHLBI NIH HHS HL052233NHLBI NIH HHS P01 HL048743NHLBI NIH HHS R01 HL052233NHLBI NIH HHS R01 HL070274NHLBI NIH HHS R01 HL080187NIDDK NIH HHS R01 DK062729NIDDK NIH HHS R01 DK085006NINDS NIH HHS P01 NS010828NINDS NIH HHS R01 NS070001
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAtorvastatinHeptanoic AcidsHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMitochondria, MuscleMuscle, SkeletalPyrrolesReactive Oxygen SpeciesTranscription FactorsAtorvastatinHeptanoic AcidsHydroxymethylglutaryl-CoA Reductase Inhibitorsperoxisome-proliferator-activated receptor-gamma coactivator-1PyrrolesReactive Oxygen SpeciesTranscription Factors

Identifiers

PMID21979988
PMCPMC3365272

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.