Evidence map›Paper›PMID 21979821›Full record

ArticleJournal of addiction medicine2012

Acute care hospital utilization among medical inpatients discharged with a substance use disorder diagnosis.

Alexander Y Walley, Michael Paasche-Orlow, Eugene C Lee, Shaula Forsythe, Veerappa K Chetty, Suzanne Mitchell, Brian W Jack

Abstract read
In one paragraph

Article in Journal of addiction medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. Inpatient utilization among Medicaid members with substance use disorder in Oregon.Substance abuse treatment, prevention, and policy · 2026
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  13. Observational
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  16. Health-related quality of life measures as predictors for recurrent hospitalization and mortality among patients in heroin-assisted treatment.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexander Y WalleyClinical Addiction Research and Education Unit, Section of General Internal Medicine, Boston University School of Medicine, 801 Massachusetts Ave, 2nd Floor, Boston, MA 02118, USA. awalley@bu.edu
Michael Paasche-Orlow
Eugene C Lee
Shaula Forsythe
Veerappa K Chetty
Suzanne Mitchell
Brian W Jack

Funding

A RCT to Reduce Cardiopulmonary RehospitalizationsR01HL081307 · NHLBI · BOSTON MEDICAL CENTER · PI JACK, BRIAN WILLIAM · 2005 to 2009
$3.7M
Testing the Re-Engineered Hospital DischargeU18HS015905 · AHRQ · BOSTON MEDICAL CENTER · PI JACK, BRIAN WILLIAM · 2005 to 2006
$291k
AHRQ HHS U18 HS015905AHRQ HHS UC1 HS014289NHLBI NIH HHS 1 R01 HL081307-01NHLBI NIH HHS R01 HL081307
6 · The paper itself

Abstract

objectiveHospital discharge may be an opportunity to intervene among patients with substance use disorders to reduce subsequent hospital utilization. This study determined whether having a substance use disorder diagnosis was associated with subsequent acute care hospital utilization.

methodsWe conducted an observational cohort study among 738 patients on a general medical service at an urban, academic, safety-net hospital. The main outcomes were rate and risk of acute care hospital utilization (emergency department visit or hospitalization) within 30 days of discharge. The main independent variable was presence of a substance use disorder primary or secondary discharge diagnosis code at the index hospitalization.

resultsAt discharge, 17% of subjects had a substance use disorder diagnosis. These patients had higher rates of recurrent acute care hospital utilization than patients without substance use disorder diagnoses (0.63 vs 0.32 events per subject at 30 days, P < 0.01) and increased risk of any recurrent acute care hospital utilization (33% vs 22% at 30 days, P < 0.05). In adjusted Poisson regression models, the incident rate ratio at 30 days was 1.49 (95% confidence interval, 1.12-1.98) for patients with substance use disorder diagnoses compared with those without. In subgroup analyses, higher utilization was attributable to those with drug diagnoses or a combination of drug and alcohol diagnoses, but not to those with exclusively alcohol diagnoses.

conclusionsMedical patients with substance use disorder diagnoses, specifically those with drug use-related diagnoses, have higher rates of recurrent acute care hospital utilization than those without substance use disorder diagnoses.

Indexed as

AdultAgedAlcoholismCohort StudiesComorbidityEmergency Service, HospitalFemaleHumansMaleMassachusettsMiddle AgedPatient DischargePatient ReadmissionRisk FactorsSubstance-Related DisordersUtilization Review

Identifiers

PMID21979821
PMCPMC6034987

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.