ReviewThrombosis and haemostasis2011
The problem of accelerated atherosclerosis in systemic lupus erythematosus: insights into a complex co-morbidity.
Review in Thrombosis and haemostasis, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Miscarriage and future maternal cardiovascular disease: a systematic review and meta-analysis.Heart (British Cardiac Society) · 2013Pooled it
- Antiphospholipid Antibodies Are Major Risk Factors for Non-Thrombotic Cardiac Complications in Systemic Lupus Erythematosus.Biomedicines · 2024Article
- The why and how of adaptive immune responses in ischemic cardiovascular disease.Nature cardiovascular research · 2022Article
- Expression and Significance of Programmed Death-1 and Its Ligands in the Accelerated Formation of Atherosclerosis in an Induced Murine Lupus Model.BioMed research international · 2022Article
- Causal association between systemic lupus erythematosus and the risk of dementia: A Mendelian randomization study.Frontiers in immunology · 2022Article
- Association between serum total antioxidant status and flow-mediated dilation in patients with systemic lupus erythematosus: an observational study.Anatolian journal of cardiology · 2015Observational
- IRF5 deficiency ameliorates lupus but promotes atherosclerosis and metabolic dysfunction in a mouse model of lupus-associated atherosclerosis.Journal of immunology (Baltimore, Md. : 1950) · 2015Article
- Cardiovascular involvement in autoimmune diseases.BioMed research international · 2014Review
- Atherosclerosis in systemic lupus erythematosus.Journal of cardiovascular pharmacology · 2013Review
- Th17/Treg imbalance induced by increased incidence of atherosclerosis in patients with systemic lupus erythematosus (SLE).Clinical rheumatology · 2013Article
- Adaptive immunity in atherogenesis: new insights and therapeutic approaches.The Journal of clinical investigation · 2013Review
- Animal models of atherosclerosis.Arteriosclerosis, thrombosis, and vascular biology · 2012Review
- Vascular disease in systemic lupus erythematosus.Autoimmune diseases · 2012Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Rheumatic autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus (SLE), are associated with antibodies to "self" antigens. Persons with autoimmune diseases, most notably SLE, are at increased risk for developing accelerated cardiovascular disease. The link between immune and inflammatory responses in the pathogenesis of cardiovascular disease has been firmly established; yet, despite our increasing knowledge, accelerated atherosclerosis continues to be a significant co-morbidity and cause of mortality in SLE. Recent animal models have been generated in order to identify mechanism(s) behind SLE-accelerated atherosclerosis. In addition, clinical studies have been designed to examine potential treatments options. This review will highlight data from recent studies of immunity in SLE and atherosclerosis and discuss the potential implications of these investigations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.