Evidence map›Paper›PMID 21978911›Full record

ReviewExperimental cell research2011

Intestinal development and differentiation.

Taeko K Noah, Bridgitte Donahue, Noah F Shroyer

Abstract readReview
In one paragraph

Review in Experimental cell research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 189 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
189citing papers in PubMed, 1 pooled it
13.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

189 citing papers in PubMed, 1 synthesis or guideline pooled it, 366 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. A preliminary study of HMGB1 defense in Crohn's disease.bioRxiv : the preprint server for biology · 2026
    Article
  7. Article
  8. ParaHox Genes Revisited: From Gut Patterning to Integrated Axial and Neural Organization in Rotifera.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Dietary Antigen Interaction with Intestinal Epithelial Cells.Current allergy and asthma reports · 2026
    Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Zinc in eye health, retinal biology and disease.Progress in retinal and eye research · 2025
    Review

129 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Taeko K NoahDivision of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Bridgitte Donahue
Noah F Shroyer
University of Cincinnati · USCincinnati Children's Hospital Medical Center · US

Funding

KLF5 regulation of intestinal development and stem cell homeostasis.R01DK092306 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI SHROYER, NOAH FREEMAN · 2011 to 2014
$1.6M
The role of ATOH1 as a tumor suppressor in colorectal cancerR01CA142826 · NCI · CINCINNATI CHILDRENS HOSP MED CTR · PI SHROYER, NOAH FREEMAN · 2010 to 2014
$1.5M
SPDEF in intestinal differentiation.R03DK084167 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI SHROYER, NOAH FREEMAN · 2009 to 2010
$151k
NCI NIH HHS R01 CA142826NIDDK NIH HHS R01 DK092306NIDDK NIH HHS R03 DK084167
6 · The paper itself

Abstract

In this review, we present an overview of intestinal development and cellular differentiation of the intestinal epithelium. The review is separated into two sections: Section one summarizes organogenesis of the small and large intestines, including endoderm and gut tube formation in early embryogenesis, villus morphogenesis, and crypt formation. Section two reviews cell fate specification and differentiation of each cell type within the intestinal epithelium. Growth factor and transcriptional networks that regulate these developmental processes are summarized.

Indexed as

Cell DifferentiationAnimalsBody PatterningEndodermHumansIntestinal MucosaIntestinesModels, BiologicalMorphogenesis

Identifiers

PMID21978911
PMCPMC3210330
OpenAlexW1981773624

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.