Evidence map›Paper›PMID 21977053›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2012

Ethnobiology and Ethnopharmacology of Lepidium meyenii (Maca), a Plant from the Peruvian Highlands.

Gustavo F Gonzales

Registry-linked trialAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05347329 (A Phase II, Randomized, Double Blind, Placebo-Controlled, Three-arm, Multi-center Clinical Trial to Investigate the Efficacy and Safety of Tongkat Ali Maca Plus for the Improvement of Sexual Well-being and Quality of Life in Men), which is not on this map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05347329 nacompletednot on this mapstarted 2019, after this paper: background citation

A Phase II, Randomized, Double Blind, Placebo-Controlled, Three-arm, Multi-center Clinical Trial to Investigate the Efficacy and Safety of Tongkat Ali Maca Plus for the Improvement of Sexual Well-being and Quality of Life in Men

TypeinterventionalSponsorNatural Wellness EgyptRan2019 to 2020Enrolled197ConditionsErectile DysfunctionArmsTongkat Ali Maca Plus
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effects of Maca (Nutrients · 2024
    Pooled it
  3. Review
  4. Article
  5. Maca (Foods (Basel, Switzerland) · 2026
    Review
  6. Purification of Lepidilines A, B, C, and D fromMolecules (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Anticonvulsant Effects of SyntheticMolecules (Basel, Switzerland) · 2025
    Article
  12. Global Research Status of Maca (Drug design, development and therapy · 2025
    Article
  13. Synergism of Specific Maca Phenotypes (Molecules (Basel, Switzerland) · 2024
    Article
  14. Effects of Chicory (Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. The Distribution of Glucosinolates in Different Phenotypes ofInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Gustavo F GonzalesDepartment of Biological and Physiological Sciences, Faculty of Sciences and Philosophy and High Altitude Research Institute, Universidad Peruana Cayetano Heredia, Honorio Delgado 430, Lima 31, Peru.

Funding

Respiratory, reproductive, and other effects of air pollution and high altitudeD43TW005746 · FIC · EMORY UNIVERSITY · PI STEENLAND, NELSON K · 2001 to 2012
$1.9M
FIC NIH HHS D43 TW005746
6 · The paper itself

Abstract

Lepidium meyenii (maca) is a Peruvian plant of the Brassicaceae family cultivated for more than 2000 years, which grows exclusively in the central Andes between 4000 and 4500 m altitude. Maca is used as a food supplement and also for its medicinal properties described traditionally. Since the 90s of the XX century, an increasing interest in products from maca has been observed in many parts of the world. In the last decade, exportation of maca from Peru has increased from 1,415,000 USD in 2001 to USD 6,170,000 USD in 2010. Experimental scientific evidence showed that maca has nutritional, energizer, and fertility-enhancer properties, and it acts on sexual dysfunctions, osteoporosis, benign prostatic hyperplasia, memory and learning, and protects skin against ultraviolet radiation. Clinical trials showed efficacy of maca on sexual dysfunctions as well as increasing sperm count and motility. Maca is a plant with great potential as an adaptogen and appears to be promising as a nutraceutical in the prevention of several diseases.

Identifiers

PMID21977053
PMCPMC3184420

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.