Evidence map›Paper›PMID 21977033›Full record

ArticleJournal of oncology2012

Tumor angiogenesis as a target for dietary cancer prevention.

William W Li, Vincent W Li, Michelle Hutnik, Albert S Chiou

Open access · hybridAbstract read
In one paragraph

Article in Journal of oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 87 citations in OpenAlex.

  1. Article
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  8. Article
  9. Molecular Targets of Natural Compounds with Anti-Cancer Properties.International journal of molecular sciences · 2021
    Review
  10. Article
  11. Implications of flavonoids as potential modulators of cancer neovascularity.Journal of cancer research and clinical oncology · 2020
    Review
  12. Lipedema-Pathogenesis, Diagnosis, and Treatment Options.Deutsches Arzteblatt international · 2020
    Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

William W LiThe Angiogenesis Foundation, One Broadway, 14th Floor, Cambridge, MA 02142, USA.
Vincent W Li
Michelle Hutnik
Albert S Chiou
Angiogenesis Foundation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Between 2000 and 2050, the number of new cancer patients diagnosed annually is expected to double, with an accompanying increase in treatment costs of more than $80 billion over just the next decade. Efficacious strategies for cancer prevention will therefore be vital for improving patients' quality of life and reducing healthcare costs. Judah Folkman first proposed antiangiogenesis as a strategy for preventing dormant microtumors from progressing to invasive cancer. Although antiangiogenic drugs are now available for many advanced malignancies (colorectal, lung, breast, kidney, liver, brain, thyroid, neuroendocrine, multiple myeloma, myelodysplastic syndrome), cost and toxicity considerations preclude their broad use for cancer prevention. Potent antiangiogenic molecules have now been identified in dietary sources, suggesting that a rationally designed antiangiogenic diet could provide a safe, widely available, and novel strategy for preventing cancer. This paper presents the scientific, epidemiologic, and clinical evidence supporting the role of an antiangiogenic diet for cancer prevention.

Identifiers

PMID21977033
PMCPMC3184418
OpenAlexW1963681473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.