Evidence map›Paper›PMID 21976765›Full record

ArticleJournal of clinical microbiology2011

A novel flucytosine-resistant yeast species, Candida pseudoaaseri, causes disease in a cancer patient.

Roland Pfüller, Yvonne Gräser, Marcel Erhard, Marizeth Groenewald

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The Fungal Cell Wall:Frontiers in microbiology · 2019
    Review
  5. Recent Taxonomic Developments withCurrent fungal infection reports · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Roland PfüllerMikrobiologisches Labor, Medizinisch-Diagnostische Institute, Berlin, Germany.
Yvonne Gräser
Marcel Erhard
Marizeth Groenewald
bioMérieux (France) · FRCharité - Universitätsmedizin Berlin · DEWesterdijk Fungal Biodiversity Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some members of the genus Candida are among the most common human fungal pathogens and cause serious diseases especially in immunocompromised people. A yeast was isolated from a blood culture from an immunocompromised cancer patient who suffered from acute pneumonia. The growth characteristics of the yeast on CHROMagar Candida were similar to those of Candida tropicalis, whereas the API ID 32C system identified the yeast as Candida silvicola. On the basis of the nucleotide divergence in the D1/D2 domain of the 26S nuclear rRNA (nrRNA) gene, as well as the internal transcribed spacer (ITS) domain of the nrRNA gene region, a new species, Candida pseudoaaseri sp. nov. with type strain VK065094 (CBS 11170(T)), which was found to be closely related to Candida aaseri, is proposed. While C. aaseri strains were susceptible to all tested antifungals, the new species is resistant to flucytosine and may also be distinguished from C. aaseri by its ability to assimilate l-rhamnose, whereas its colony morphology on CHROMagar Candida may be helpful for differentiation.

Indexed as

Drug Resistance, FungalAntifungal AgentsCandidaCandidemiaCluster AnalysisDNA, FungalDNA, RibosomalDNA, Ribosomal SpacerFlucytosineGenes, rRNAHumansImmunocompromised HostMaleMiddle AgedMolecular Sequence DataMycological Typing TechniquesAntifungal AgentsDNA, FungalDNA, RibosomalDNA, Ribosomal SpacerFlucytosineRNA, FungalRNA, RibosomalRNA, ribosomal, 26S

Identifiers

PMID21976765
PMCPMC3233011
OpenAlexW2155433896

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.