Evidence map›Paper›PMID 21976646›Full record

ArticleJournal of virology2011

Indications that live poultry markets are a major source of human H5N1 influenza virus infection in China.

Xiu-Feng Wan, Libo Dong, Yu Lan, Li-Ping Long, Cuiling Xu, Shumei Zou, Zi Li, Leying Wen, Zhipeng Cai, Wei Wang and 19 more

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 159 citations in OpenAlex.

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  13. Article
  14. Live animal markets: Identifying the origins of emerging infectious diseases.Current opinion in environmental science & health · 2022
    Review
  15. Analyzing Strategies for Containing Avian Influenza.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. A call for global monitoring of WASH in wet markets.The Lancet. Planetary health · 2020
    Article

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 4 institutions in 2 countries.

Xiu-Feng WanState Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, 155 Changbai Road, Beijing 102206, China.
Libo Dong
Yu Lan
Li-Ping Long
Cuiling Xu
Shumei Zou
Zi Li
Leying Wen
Zhipeng Cai
Wei Wang
Xiaodan Li
Fan Yuan
Hongtao Sui
Ye Zhang
Jie Dong
Shanhua Sun
Yan Gao
Min Wang
Tian Bai
Lei Yang
Dexin Li
Weizhong Yang
Hongjie Yu
Shiwen Wang
Zijian Feng
Yu Wang
Yuanji Guo
Richard J Webby
Yuelong Shu
National Institute for Viral Disease Control and Prevention · CNChinese Center For Disease Control and Prevention · CNMississippi State University · USSt. Jude Children's Research Hospital · US

Funding

Virology &ImmunologyU19AI051915 · NIAID · NATIONAL CENTER FOR AIDS/STD CONTROL AND PREVENTION · PI GAO, GEORGE FU · 2002 to 2009
$21.6M
DEVELOPING SUSTAINABLE INFLUENZA SURVEILLANCE NETWORKS AND RESPONSE TO AVIAN AND U51IP000334 · IP · NATL INST OF VIRAL DISEASE CONTROL/PREV · PI SHU, YUELONG · 2009 to 2013
$4.2M
Prediction of influenza antigenic variants using a novel sparse multitask learninRC1AI086830 · NIAID · MISSISSIPPI STATE UNIVERSITY · PI WAN, XIUFENG HENRY · 2010 to 2010
$413k
NCIRD CDC HHS U51 IP000334NCIRD CDC HHS U51/IP000334-02NIAID NIH HHS HHSN266200700005CNIAID NIH HHS RC1 AI086830NIAID NIH HHS RC1AI086830NIAID NIH HHS U19 AI051915NIAID NIH HHS U19 AI051915-05S1
6 · The paper itself

Abstract

Human infections of H5N1 highly pathogenic avian influenza virus have continued to occur in China without corresponding outbreaks in poultry, and there is little conclusive evidence of the source of these infections. Seeking to identify the source of the human infections, we sequenced 31 H5N1 viruses isolated from humans in China (2005 to 2010). We found a number of viral genotypes, not all of which have similar known avian virus counterparts. Guided by patient questionnaire data, we also obtained environmental samples from live poultry markets and dwellings frequented by six individuals prior to disease onset (2008 and 2009). H5N1 viruses were isolated from 4 of the 6 live poultry markets sampled. In each case, the genetic sequences of the environmental and corresponding human isolates were highly similar, demonstrating a link between human infection and live poultry markets. Therefore, infection control measures in live poultry markets are likely to reduce human H5N1 infection in China.

Indexed as

Environmental MicrobiologyAdolescentAdultAnimalsChildChild, PreschoolChinaCluster AnalysisGenotypeHumansInfluenza A Virus, H5N1 SubtypeInfluenza, HumanMiddle AgedMolecular EpidemiologyMolecular Sequence DataPoultryRNA, Viral

Identifiers

PMID21976646
PMCPMC3233185
OpenAlexW2135659478

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.