Evidence map›Paper›PMID 21976608›Full record

ReviewClinical microbiology reviews2011

Serratia infections: from military experiments to current practice.

Steven D Mahlen

Open access · greenAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 308 papers.

0numbers the graph read from it
0cells of the map it votes in
308citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

308 citing papers in PubMed, 608 citations in OpenAlex.

  1. Article
  2. Spread of carbapenemase-producingEmerging microbes & infections · 2026
    Article
  3. Occurrence ofJournal of veterinary research · 2026
    Article
  4. A standardized workflow for typing S. marcescens outbreaks using FT-IR spectroscopy.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Serratia Bacteraemia in the North Denmark Region: A Population-Based Study (2010-2024).APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026
    Article
  10. Article
  11. Clinical Analysis ofPathogens (Basel, Switzerland) · 2026
    Article
  12. Harnessing a Lytic (Biology · 2026
    Article
  13. Article
  14. Drug repositioning as an antivirulence strategy: Ketoprofen targets quorum sensing and biofilm in Serratia sp.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  15. Draft genome sequence ofMicrobiology resource announcements · 2026
    Article
  16. From Environmental Organism to Nosocomial Threat:Antibiotics (Basel, Switzerland) · 2026
    Review
  17. Article
  18. Prevalence and activity of class II microcins inApplied and environmental microbiology · 2026
    Article
  19. Article
  20. Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2026
    Review

248 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Steven D MahlenDepartment of Pathology and Area Laboratory Services, Madigan Healthcare System, Tacoma, WA 98143, USA. steven.mahlen@us.army.mil
Madigan Army Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serratia species, in particular Serratia marcescens, are significant human pathogens. S. marcescens has a long and interesting taxonomic, medical experimentation, military experimentation, and human clinical infection history. The organisms in this genus, particularly S. marcescens, were long thought to be nonpathogenic. Because S. marcescens was thought to be a nonpathogen and is usually red pigmented, the U.S. military conducted experiments that attempted to ascertain the spread of this organism released over large areas. In the process, members of both the public and the military were exposed to S. marcescens, and this was uncovered by the press in the 1970s, leading to U.S. congressional hearings. S. marcescens was found to be a certain human pathogen by the mid-1960s. S. marcescens and S. liquefaciens have been isolated as causative agents of numerous outbreaks and opportunistic infections, and the association of these organisms with point sources such as medical devices and various solutions given to hospitalized patients is striking. Serratia species appear to be common environmental organisms, and this helps to explain the large number of nosocomial infections due to these bacteria. Since many nosocomial infections are caused by multiply antibiotic-resistant strains of S. marcescens, this increases the danger to hospitalized patients, and hospital personnel should be vigilant in preventing nosocomial outbreaks due to this organism. S. marcescens, and probably other species in the genus, carries several antibiotic resistance determinants and is also capable of acquiring resistance genes. S. marcescens and S. liquefaciens are usually identified well in the clinical laboratory, but the other species are rare enough that laboratory technologists may not recognize them. 16S rRNA gene sequencing may enable better identification of some of the less common Serratia species.

Indexed as

Anti-Bacterial AgentsCross InfectionHumansMilitary PersonnelSerratia InfectionsSerratia liquefaciensSerratia marcescensUnited StatesAnti-Bacterial Agents

Identifiers

PMID21976608
PMCPMC3194826
OpenAlexW2123712967

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.