ReviewClinical microbiology reviews2011
Clinical manifestations, diagnosis, and treatment of Mycobacterium haemophilum infections.
Review in Clinical microbiology reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
59 citing papers in PubMed, 161 citations in OpenAlex.
- CutaneousClinical case reports · 2026Article
- DisseminatedJournal of clinical tuberculosis and other mycobacterial diseases · 2026Article
- Expanding the Clinical Spectrum ofOpen forum infectious diseases · 2026Article
- A Novel Presentation of Mycobacterium haemophilum Cutaneous Infection: A Diagnostic Challenge.Acta dermato-venereologica · 2026Article
- Case Report:Frontiers in medicine · 2026Article
- Article
- Multifocal Cutaneous and MusculoskeletalCase reports in transplantation · 2026Article
- Article
- GATA2 mutation is associated with immune dysfunction and increased Mycobacterium haemophilum susceptibility in immunocompromised individuals.JCI insight · 2025Article
- The Brief Case: Complexity of laboratory diagnosis ofJournal of clinical microbiology · 2025Review
- Article
- Paediatric cervicofacial lymphadenitis caused by non-tuberculous mycobacteria: nation-wide overview in the period 2000-2020.BMC pediatrics · 2025Article
- Haemophagocytic lymphohistiocytosis driven by disseminatedSkin health and disease · 2025Article
- Diagnosis of nontuberculous mycobacterial infections using genomics and artificial intelligence-machine learning approaches: scope, progress and challenges.Frontiers in microbiology · 2025Review
- Machine Learning-Based Interpretable Screening for Osteoporosis in Tuberculosis Spondylitis Patients Using Blood Test Data: Development and External Validation of a Novel Web-Based Risk Calculator with Explainable Artificial Intelligence (XAI).Infection and drug resistance · 2025Article
- Article
- Review of methods for detection and characterization of non-tuberculous mycobacteria in aquatic organisms.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024Review
- Neurological manifestations of nontuberculous mycobacteria in adults: case series and review of the literature.Frontiers in neurology · 2024Article
- A Systemic Lupus Erythematosus Patient with CutaneousAnnals of dermatology · 2023Article
- Ocular Mycobacterium haemophilum infection originating in the cornea: a case report.BMC infectious diseases · 2023Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mycobacterium haemophilum is a slowly growing acid-fast bacillus (AFB) belonging to the group of nontuberculous mycobacteria (NTM) frequently found in environmental habitats, which can colonize and occasionally infect humans and animals. Several findings suggest that water reservoirs are a likely source of M. haemophilum infections. M. haemophilum causes mainly ulcerating skin infections and arthritis in persons who are severely immunocompromised. Disseminated and pulmonary infections occasionally occur. The second at-risk group is otherwise healthy children, who typically develop cervical and perihilar lymphadenitis. A full diagnostic regimen for the optimal detection of M. haemophilum includes acid-fast staining, culturing at two temperatures with iron-supplemented media, and molecular detection. The most preferable molecular assay is a real-time PCR targeting an M. haemophilum-specific internal transcribed spacer (ITS), but another approach is the application of a generic PCR for a mycobacterium-specific fragment with subsequent sequencing to identify M. haemophilum. No standard treatment guidelines are available, but published literature agrees that immunocompromised patients should be treated with multiple antibiotics, tailored to the disease presentation and underlying degree of immune suppression. The outcome of M. haemophilum cervicofacial lymphadenitis in immunocompetent patients favors surgical intervention rather than antibiotic treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.