ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2011
Multiple arithmetic operations in a single neuron: the recruitment of adaptation processes in the cricket auditory pathway depends on sensory context.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Neuronal processing of complex sounds in the prothoracic ganglion of a bushcricket.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Article
- The electrogenicity of the NaeLife · 2025Article
- Regression to the mean explains perception of action consequences.Proceedings. Biological sciences · 2025Article
- Sound level context modulates neural activity in the human brainstem.Scientific reports · 2021Article
- A small, computationally flexible network produces the phenotypic diversity of song recognition in crickets.eLife · 2021Article
- Neural Responses and Perceptual Sensitivity to Sound Depend on Sound-Level Statistics.Scientific reports · 2020Article
- Online Detection of Multiple Stimulus Changes Based on Single Neuron Interspike Intervals.Frontiers in computational neuroscience · 2019Article
- Aging Affects Adaptation to Sound-Level Statistics in Human Auditory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Stimulus-specific adaptation in a recurrent network model of primary auditory cortex.PLoS computational biology · 2017Article
- Sensitivity of rat inferior colliculus neurons to frequency distributions.Journal of neurophysiology · 2015Article
- Statistical context shapes stimulus-specific adaptation in human auditory cortex.Journal of neurophysiology · 2015Article
- A neural mechanism for time-window separation resolves ambiguity of adaptive coding.PLoS biology · 2015Article
- Spiking neural circuits with dendritic stimulus processors : encoding, decoding, and identification in reproducing kernel Hilbert spaces.Journal of computational neuroscience · 2015Article
- Binocular misalignments elicited by altered gravity provide evidence for nonlinear central compensation.Frontiers in systems neuroscience · 2015Article
- Computational themes of peripheral processing in the auditory pathway of insects.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2015Review
- Neurobiology of acoustically mediated predator detection.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2015Article
- Subtractive, divisive and non-monotonic gain control in feedforward nets linearized by noise and delays.Frontiers in computational neuroscience · 2014Article
- Calling song signals and temporal preference functions in the cricket Teleogryllus leo.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2012Article
- Bursting neurons and ultrasound avoidance in crickets.Frontiers in neuroscience · 2012Article
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3 authors.
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Abstract
Sensory pathways process behaviorally relevant signals in various contexts and therefore have to adapt to differing background conditions. Depending on changes in signal statistics, this adjustment might be a combination of two fundamental computational operations: subtractive adaptation shifting a neuron's threshold and divisive gain control scaling its sensitivity. The cricket auditory system has to deal with highly stereotyped conspecific songs at low carrier frequencies, and likely much more variable predator signals at high frequencies. We proposed that due to the differences between the two signal classes, the operation that is implemented by adaptation depends on the carrier frequency. We aimed to identify the biophysical basis underlying the basic computational operations of subtraction and division. We performed in vivo intracellular and extracellular recordings in a first-order auditory interneuron (AN2) that is active in both mate recognition and predator avoidance. We demonstrated subtractive shifts at the carrier frequency of conspecific songs and division at the predator-like carrier frequency. Combined application of current injection and acoustic stimuli for each cell allowed us to demonstrate the subtractive effect of cell-intrinsic adaptation currents. Pharmacological manipulation enabled us to demonstrate that presynaptic inhibition is most likely the source of divisive gain control. We showed that adjustment to the sensory context can depend on the class of signals that are relevant to the animal. We further revealed that presynaptic inhibition is a simple mechanism for divisive operations. Unlike other proposed mechanisms, it is widely available in the sensory periphery of both vertebrates and invertebrates.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.