ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2011
Human primary auditory cortex follows the shape of Heschl's gyrus.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers, 3 of them syntheses that pooled it.
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Who cites it
155 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The functional foetal brain: A systematic review and meta-analysis.Developmental cognitive neuroscience · 2026Pooled it
- Brain Morphological Modifications in Congenital and Acquired Auditory Deprivation: A Systematic Review and Coordinate-Based Meta-Analysis.Frontiers in neuroscience · 2022Pooled it
- Pooled it
- Representation of pitch chroma by multi-peak spectral tuning in human auditory cortex.NeuroImage · 2015Trial
- Sulcal pleating captures functional boundaries in human visual cortex.bioRxiv : the preprint server for biology · 2026Article
- Music-selective cortex is sensitive to structure in both pitch and time.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Blindness reveals that Heschl's gyrus folding is not altered by auditory experience.bioRxiv : the preprint server for biology · 2026Article
- eXCube2: Explainable Brain-Inspired Spiking Neural Network Framework for Emotion Recognition from Audio, Visual and Multimodal Audio-Visual Data.Biomimetics (Basel, Switzerland) · 2026Article
- Aberrant network topology of cortical-subcortical circuits in schizophrenia and bipolar disorder: a graph theory study.Frontiers in psychiatry · 2026Article
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- Contentopic mapping in ventral and dorsal association cortex: The topographical organization of manipulable object information.NeuroImage · 2025Article
- Wavelet Analysis of Dual-fMRI-Hyperscanning Reveals Cooperation and Communication Dependent Effects on Interbrain Neuronal Coherence.Human brain mapping · 2025Article
- Category learning drives cortical attentional gain to diagnostic dimensions.bioRxiv : the preprint server for biology · 2025Article
- Machine learning of whole-brain resting-state fMRI signatures for individualized grading of frontal gliomas.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025Article
- Article
- Human insula neurons respond to simple sounds during passive listening.bioRxiv : the preprint server for biology · 2025Article
- Individual connectivity-based parcellations reflect functional properties of human auditory cortex.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Normative trajectories of RImaging neuroscience (Cambridge, Mass.) · 2025Article
- Duplicated Heschl's gyrus associations with phonological decoding.Brain structure & function · 2024Article
- Automatic Segmentation of Heschl Gyrus and Planum Temporale by MRICloud.Otology & neurotology open · 2024Article
95 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The primary auditory cortex (PAC) is central to human auditory abilities, yet its location in the brain remains unclear. We measured the two largest tonotopic subfields of PAC (hA1 and hR) using high-resolution functional MRI at 7 T relative to the underlying anatomy of Heschl's gyrus (HG) in 10 individual human subjects. The data reveals a clear anatomical-functional relationship that, for the first time, indicates the location of PAC across the range of common morphological variants of HG (single gyri, partial duplications, and complete duplications). In 20/20 individual hemispheres, two primary mirror-symmetric tonotopic maps were clearly observed with gradients perpendicular to HG. PAC spanned both divisions of HG in cases of partial and complete duplications (11/20 hemispheres), not only the anterior division as commonly assumed. Specifically, the central union of the two primary maps (the hA1-R border) was consistently centered on the full Heschl's structure: on the gyral crown of single HGs and within the sulcal divide of duplicated HGs. The anatomical-functional variants of PAC appear to be part of a continuum, rather than distinct subtypes. These findings significantly revise HG as a marker for human PAC and suggest that tonotopic maps may have shaped HG during human evolution. Tonotopic mappings were based on only 16 min of fMRI data acquisition, so these methods can be used as an initial mapping step in future experiments designed to probe the function of specific auditory fields.
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