Evidence map›Paper›PMID 21975550›Full record

ReviewCell adhesion & migration

The role of actin bundling proteins in the assembly of filopodia in epithelial cells.

Seema Khurana, Sudeep P George

Open access · goldAbstract readReview
In one paragraph

Review in Cell adhesion & migration. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
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  8. Review
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  11. Article
  12. Article
  13. Recapitulating Actin Module Organization in theInternational journal of molecular sciences · 2021
    Article
  14. Article
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Seema KhuranaDepartment of Biology and Biochemistry, University of Houston, Houston, TX, USA. skhurana@uh.edu
Sudeep P George
University of Houston · US

Funding

ROLE OF VILLIN IN EPITHELIAL CELL SIGNAL TRANSDUCTIONR01DK054755 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI KHURANA, SEEMA · 2000 to 2009
$3.1M
NIDDK NIH HHS DK-54755NIDDK NIH HHS R01 DK054755
6 · The paper itself

Abstract

The goal of this review is to highlight how emerging new models of filopodia assembly, which include tissue specific actin-bundling proteins, could provide more comprehensive representations of filopodia assembly that would describe more adequately and effectively the complexity and plasticity of epithelial cells.  This review also describes how the true diversity of actin bundling proteins must be considered to predict the far-reaching significance and versatile functions of filopodia in epithelial cells.

Indexed as

ActinsCarrier ProteinsCell MovementEpithelial CellsHumansMicrofilament ProteinsMicrovilliModels, MolecularNeoplasm MetastasisPseudopodiaActinsCarrier ProteinsfascinMicrofilament Proteinsvillin

Identifiers

PMID21975550
PMCPMC3218608
OpenAlexW2086097918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.