ReviewChemical Society reviews2012
Thermophilic proteins: insight and perspective from in silico experiments.
Review in Chemical Society reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed.
- AnFrontiers in chemistry · 2026Article
- Periodontopathogens degrade angiotensin I from the human renin-angiotensin system through surface-attached proteases.Scientific reports · 2025Article
- Temperature-dependent iron motion in extremophile rubredoxins - no need for 'corresponding states'.Scientific reports · 2024Article
- Article
- Life at high temperature observed in vitro upon laser heating of gold nanoparticles.Nature communications · 2022Article
- A Statistical Analysis of the Sequence and Structure of Thermophilic and Non-Thermophilic Proteins.International journal of molecular sciences · 2022Article
- Loosely-packed dynamical structures with partially-melted surface being the key for thermophilic argonaute proteins achieving high DNA-cleavage activity.Nucleic acids research · 2022Article
- Article
- Isolation and thermo-acclimation of thermophilic bacteria in hyperthermophilic fermentation system.Bioprocess and biosystems engineering · 2022Article
- Structural basis for the hyperthermostability of an archaeal enzyme induced by succinimide formation.Biophysical journal · 2021Article
- Deletion of a Peptidylprolyl Isomerase Gene Results in the Inability ofApplied and environmental microbiology · 2020Article
- Evaluating the strengths of salt bridges in the CutA1 protein using molecular dynamic simulations: a comparison of different force fields.FEBS open bio · 2019Article
- Crystal Structure and Conformational Dynamics of Pyrococcus furiosus Prolyl Oligopeptidase.Biochemistry · 2019Article
- CAP modifies the structure of a model protein from thermophilic bacteria: mechanisms of CAP-mediated inactivation.Scientific reports · 2018Article
- Ion-ion interactions in the denatured state contribute to the stabilization of CutA1 proteins.Scientific reports · 2018Article
- The extraordinary thermal stability of EstA from S. islandicus is independent of post translational modifications.Protein science : a publication of the Protein Society · 2017Article
- Critical structural fluctuations of proteins upon thermal unfolding challenge the Lindemann criterion.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Role of Proteome Physical Chemistry in Cell Behavior.The journal of physical chemistry. B · 2016Review
- Stay Wet, Stay Stable? How Internal Water Helps the Stability of Thermophilic Proteins.The journal of physical chemistry. B · 2015Article
- Role of Internal Water on Protein Thermal Stability: The Case of Homologous G Domains.The journal of physical chemistry. B · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Proteins from thermophilic and hyperthermophilic organisms are stable and function at high temperatures (50-100 °C). The importance of understanding the microscopic mechanisms underlying this thermal resistance is twofold: it is key for acquiring general clues on how proteins maintain their fold stable and for targeting those medical and industrial applications that aim at designing enzymes that can work under harsh conditions. In this tutorial review we first provide the general background of protein thermostability by specifically focusing on the structural and thermodynamic peculiarities; next, we discuss how computational studies based on Molecular Dynamics simulations can broaden and refine our knowledge on such special class of proteins.
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Registered trials
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