ArticleParkinsonism & related disorders2012
Loss of ability to work and ability to live independently in Parkinson's disease.
Article in Parkinsonism & related disorders, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prognosis in Parkinson's Disease: An Individual Patient Data Meta-Analysis of Six European Incidence Cohorts.Movement disorders : official journal of the Movement Disorder Society · 2026Pooled it
- A systematic review of loss of independence in Parkinson's disease.Journal of neurology · 2016Pooled it
- Integrating GPS and Accelerometry to Capture Life-Space Mobility in Parkinson's Disease.Sensors (Basel, Switzerland) · 2026Article
- Combined Effects of Depression, Fatigue and Cardiovascular Dysfunction on Functional Dependence Over Seven Years in Early Parkinson's Disease.Movement disorders clinical practice · 2026Article
- Parkinson's disease gait rehabilitation at scale: Insights on personalised smartphone-based music cueing.PloS one · 2026Article
- An Experimental Approach for Investigating Freezing of Gait in Parkinson's Disease Using Virtual Reality and Neural Sensing: A Pilot Study.Sensors (Basel, Switzerland) · 2025Article
- Predicting Ambulatory Capacity in Parkinson's Disease to Analyze Progression, Biomarkers, and Trial Design.Movement disorders : official journal of the Movement Disorder Society · 2023Observational
- The impact of Parkinson's disease severity on performance of activities of daily living: an observational study.Revista de neurologia · 2023Observational
- Nomogram to Predict the Probability of Functional Dependence in Early Parkinson's Disease.Journal of Parkinson's disease · 2023Article
- Successful implementation of technology in the management of Parkinson's disease: Barriers and facilitators.Clinical parkinsonism & related disorders · 2023Review
- Predictors of Loss of Functional Independence in Parkinson's Disease: Results from the COPPADIS Cohort at 2-Year Follow-Up and Comparison with a Control Group.Diagnostics (Basel, Switzerland) · 2021Article
- Association between Cardiac Autonomic Control and Postural Control in Patients with Parkinson's Disease.International journal of environmental research and public health · 2020Article
- The impact of freezing of gait on functional dependency in Parkinson's disease with regard to motor phenotype.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Article
- Parkinsonian Symptoms, Not Dyskinesia, Negatively Affect Active Life Participation of Dyskinetic Patients with Parkinson's Disease.Tremor and other hyperkinetic movements (New York, N.Y.) · 2020Article
- Remnants of Cardinal Symptoms of Parkinson's Disease, Not Dyskinesia, Are Problematic for Dyskinetic Patients Performing Activities of Daily Living.Frontiers in neurology · 2019Article
- Anxiety and Levodopa Equivalent Daily Dose Are Potential Predictors of Sleep Quality in Patients With Parkinson Disease in Taiwan.Frontiers in neurology · 2019Article
- Inventory of real world data sources in Parkinson's disease.BMC neurology · 2017Review
- Predictors of functional dependency in Parkinson's disease.Movement disorders : official journal of the Movement Disorder Society · 2016Article
- Active aging for individuals with Parkinson's disease: definitions, literature review, and models.Parkinson's disease · 2014Review
- Parkinson's disease: how is employment affected?Irish journal of medical science · 2013Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectiveAbility to work and live independently is of particular concern for patients with Parkinson's disease (PD). We studied a series of PD patients able to work or live independently at baseline, and evaluated potential risk factors for two separate outcomes: loss of ability to work and loss of ability to live independently.
methodsThe series comprised 495 PD patients followed prospectively. Ability to work and ability to live independently were based on clinical interview and examination. Cox regression models adjusted for age and disease duration were used to evaluate associations of baseline characteristics with loss of ability to work and loss of ability to live independently.
resultsHigher UPDRS dyskinesia score, UPDRS instability score, UPDRS total score, Hoehn and Yahr stage, and presence of intellectual impairment at baseline were all associated with increased risk of future loss of ability to work and loss of ability to live independently (P ≤ 0.0033). Five years after initial visit, for patients ≤70 years of age with a disease duration ≤4 years at initial visit, 88% were still able to work and 90% to live independently. These estimates worsened as age and disease duration at initial visit increased; for patients >70 years of age with a disease duration >4 years, estimates at 5 years were 43% able to work and 57% able to live independently.
conclusionsThe information provided in this study can offer useful information for PD patients in preparing for future ability to perform activities of daily living.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.