Evidence map›Paper›PMID 21975198›Full record

ArticleNeurology2011

Meralgia paresthetica: relation to obesity, advanced age, and diabetes mellitus.

Thomas J Parisi, Jay Mandrekar, P James B Dyck, Christopher J Klein

Open access · bronzeAbstract read
In one paragraph

Article in Neurology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 120 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Meralgia paraesthetica.BJA education · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Meralgia Paresthetica: Relevance, Diagnosis, and Treatment.Deutsches Arzteblatt international · 2023
    Review
  20. Chiropractic management of bilateral meralgia paresthetica: a case report.The Journal of the Canadian Chiropractic Association · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Thomas J ParisiDepartment of Graduate Medicine, Mayo Medical School, 200 First Street SW, Rochester, MN 55905, USA.
Jay Mandrekar
P James B Dyck
Christopher J Klein
Mayo Clinic · US

Funding

Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
DIABETIC NEUROPATHY STUDYR01NS036797 · NINDS · MAYO CLINIC ROCHESTER · PI DYCK, PETER JAMES · 1997 to 2008
$6.8M
Identification of Genetic Causes of Hereditary Sensory and Autonomic NeuropathiesK08NS065007 · NINDS · MAYO CLINIC ROCHESTER · PI KLEIN, CHRISTOPHER · 2009 to 2013
$855k
NIA NIH HHS 9R01-AG034676-45NIA NIH HHS R01 AG034676NINDS NIH HHS K08-NS065007-01A1NINDS NIH HHS NS36797
6 · The paper itself

Abstract

objectiveTo determine the incidence of meralgia paresthetica (MP) and its relationship to diabetes mellitus (DM) and obesity.

methodsA population-based study was performed within Olmstead County Minnesota, from January 1, 1990, to December 31, 1999. MP incidence and its association with age, gender, body mass index (BMI), and DM were reviewed.

resultsA total of 262 patients with MP, 262 normal controls, and 262 BMI-matched normal controls with mean age of 50 years were identified (51% men). The age- and sex-adjusted incidence of MP was 32.6 per 100,000 patient years, whereas the incidence of MP in people with DM was 247 per 100,000 patient years, 7 times the occurrence of MP in the general population. Of the patients with MP, 28% had DM vs 17% of BMI-matched controls and the majority of people with MP developed DM after the diagnosis of MP. Patients with MP are 2 times more likely to develop DM (odds ratio 2, 95% confidence interval 1.3-3.0, p = 0.0027). The mean BMI of patients with MP (30.1 kg/m(2), obese class I) was significantly higher than that of age- and gender-matched controls (27.3 kg/m(2), overweight). MP incidence increased 12.9 per 100,000 patient years in the hemidecade study period with an associated increase in both BMI (2.2 kg/m(2)) and average age (3 years).

conclusionsMP is a frequent painful neuropathy associated with obesity, advancing age, and DM. The incidence rate of MP is predicted to increase as these demographics increase in world populations. Because MP associates with DM beyond weight- and age-matched controls, more aggressive counseling of these patients in prevention of DM may be warranted.

Indexed as

AgingBody Mass IndexCommunity Health PlanningDiabetes MellitusFemaleFemoral NeuropathyHumansIncidenceMaleMiddle AgedNerve Compression SyndromesObesityRetrospective Studies

Identifiers

PMID21975198
PMCPMC3198972
OpenAlexW2167102255

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.