Trial reportJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2011
Clinical role of the Duke Activity Status Index in the selection of the optimal type of stress myocardial perfusion imaging study in patients with known or suspected ischemic heart disease.
Trial report in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 34 citations in OpenAlex.
- Pilot study to evaluate the safety and effectiveness of etidronate treatment for arterial calcification due to deficiency of CD73 (ACDC).Vascular medicine (London, England) · 2024Trial
- Safety and efficacy of RT234 vardenafil inhalation powder on exercise parameters in pulmonary arterial hypertension: phase II, dose-escalation study design.Respiratory research · 2022Trial
- Safety and feasibility of adjunctive regadenoson injection at peak exercise during exercise myocardial perfusion imaging: The Both Exercise and Regadenoson Stress Test (BERST) trial.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013Trial
- A strategy of symptom-limited exercise with regadenoson-as-needed for stress myocardial perfusion imaging: a randomized controlled trial.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013Trial
- Aortic pulse wave analysis and functional capacity of heart transplantation candidates: a pilot study.Scientific reports · 2024Article
- Usefulness of the Duke Activity Status Index to Assess Exercise Capacity and Predict Risk Stratification in Patients with Pulmonary Arterial Hypertension.Journal of clinical medicine · 2023Article
- Comparative efficiency of exercise stress testing with and without stress-only myocardial perfusion imaging in patients with low-risk chest pain.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Choosing exercise or pharmacologic stress imaging, or exercise ECG testing alone: How to decide.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- The role of treadmill exercise testing in women.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Review
- Relationships between self-reported and performance-based measures of functional capacity in individuals with chronic stroke.Journal of physical therapy science · 2016Article
- Duke Activity Status Index for cardiovascular diseases: validation of the Portuguese translation.Arquivos brasileiros de cardiologia · 2014Article
- Provisional use of myocardial perfusion imaging in patients undergoing exercise stress testing: a worthy concept fraught with challenges.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013Article
- The WOMENs trial: how should I interpret the results?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2012Article
- Anesthesia-related unexpected cardiac arrest- What are we doing wrong on preoperative evaluation?Porto biomedical journalArticle
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExercise treadmill stress myocardial perfusion imaging (MPI) with single photon emission computed tomography is commonly used to evaluate the extent and severity of inducible ischemia as well as to risk stratify patients with suspected and known coronary artery disease (CAD). Failure to reach adequate stress, defined as not attaining age-appropriate metabolic equivalents (METs), can underestimate the extent and severity of ischemic heart disease, resulting in false negative results. This study evaluates the efficacy of the Duke Activity Status Index (DASI), a simple self-administered 12-item questionnaire, as a predictor of METs achieved by treadmill stress testing.
methodsThe DASI was prospectively administered to 200 randomly selected men and women referred to the nuclear cardiology laboratory at New York University Langone Medical Center for stress MPI. Each patient was asked to complete the 12-item DASI questionnaire independently. 136 patients underwent treadmill exercise with MPI and 64 had pharmacologic stress with MPI. The association between exercise capacity in METs as estimated by the DASI questionnaire and performance on the Bruce treadmill protocol in METS was compared using chi-square statistics.
resultsOver 70% of those patients whose DASI score predicted the ability to perform <10 METs were unable to exercise beyond stage 2 of the Bruce protocol (7 METs). For those whose DASI score predicted ability to perform >12.5 METs, over 80% of patients reached >stage 2 of the Bruce protocol with 40% reaching beyond stage 3 (10 METs). When patient age was incorporated into the calculation, a more linear relationship was observed between predicted and obtained METs.
conclusionThe DASI is a simple self-administered questionnaire which is a useful pretest tool to determine a patient's ability to achieve appropriate METs. In the nuclear cardiology laboratory, the DASI has the potential to guide selection of exercise treadmill vs pharmacologic stress and ultimately improve laboratory efficiency.
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