ArticleJournal of proteome research2012
Proteomic profiling of the influence of iron availability on Cryptococcus gattii.
Article in Journal of proteome research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Corrected and republished from: "Extracellular Vesicle Formation inInfection and immunity · 2024Article
- Article
- Identification of Disease-Associated Cryptococcal Proteins Reactive With Serum IgG From Cryptococcal Meningitis Patients.Frontiers in immunology · 2021Article
- Article
- Indole contributes to tetracycline resistance via the outer membrane protein OmpN in Vibrio splendidus.World journal of microbiology & biotechnology · 2020Article
- Characterization of the Potential ProbioticIranian journal of biotechnology · 2020Article
- Article
- The influence of iron on the proteomic profile of Chromobacterium violaceum.BMC microbiology · 2014Article
- Proteomic profile of Cryptococcus neoformans biofilm reveals changes in metabolic processes.Journal of proteome research · 2014Article
- Conflicting interests in the pathogen-host tug of war: fungal micronutrient scavenging versus mammalian nutritional immunity.PLoS pathogens · 2014Review
- Proteogenomic analysis of pathogenic yeast Cryptococcus neoformans using high resolution mass spectrometry.Clinical proteomics · 2014Article
- Identification of genes expressed by Cryptococcus gattii during iron deprivation.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2014Article
- An encapsulation of iron homeostasis and virulence in Cryptococcus neoformans.Trends in microbiology · 2013Review
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
Iron is essential and ubiquitous in living organisms. The competition for this micronutrient between the host and its pathogens has been related to disease establishment. Cryptococcus gattii is an encapsulated yeast that causes cryptococcosis mainly in immunocompetent individuals. In this study, we analyzed the proteomic profile of the C. gattii R265 Vancouver Island isolate under iron-depleted and -repleted conditions by multidimensional protein identification technology (MudPIT) and by 2D-GE. Proteins and key mechanisms affected by alteration of iron levels such as capsule production, cAMP-signaling pathway, response to stress, and metabolic pathways related to mitochondrial function were identified. Our results also show both proteomic methodologies employed to be complementary.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.