ArticlePloS one2011
Positive Darwinian selection in the piston that powers proton pumps in complex I of the mitochondria of Pacific salmon.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed, 102 citations in OpenAlex.
- Climate-associated natural selection in the human mitochondrial genome.Molecular biology and evolution · 2026Article
- Mitogenomic Characterization ofBiology · 2025Article
- Mitonuclear Coevolution in Bumblebees (Bombus): Genomic Signatures and Its Role in Climatic Niche Adaptation.Genome biology and evolution · 2025Article
- Influence of life-history traits on mitochondrial DNA substitution rates exceeds that of metabolic rates in teleost fishes.Current zoology · 2025Article
- Comparative mitogenomic analysis of subterranean and surface amphipods (Crustacea, Amphipoda) with special reference to the family Crangonyctidae.BMC genomics · 2024Article
- Phylogeography using mitogenomes: A rare Dipodidae,Ecology and evolution · 2022Article
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- Positive selection over the mitochondrial genome and its role in the diversification of gentoo penguins in response to adaptation in isolation.Scientific reports · 2022Article
- Molecular Phylogeny and Adaptive Mitochondrial DNA Evolution of Salmonids (Pisces: Salmonidae).Frontiers in genetics · 2022Article
- Molecular assessment of proteins encoded by the mitochondrial genome ofBiochemistry and biophysics reports · 2021Article
- Integrative genomic phylogeography reveals signs of mitonuclear incompatibility in a natural hybrid goby population.Evolution; international journal of organic evolution · 2021Article
- Patterns of Natural Selection on Mitochondrial Protein-Coding Genes in Lungless Salamanders: Relaxed Purifying Selection and Presence of Positively Selected Codon Sites in the Family Plethodontidae.International journal of genomics · 2021Article
- Genetic hitchhiking, mitonuclear coadaptation, and the origins of mt DNA barcode gaps.Ecology and evolution · 2020Article
- Signals of selection in the mitogenome provide insights into adaptation mechanisms in heterogeneous habitats in a widely distributed pelagic fish.Scientific reports · 2020Article
- Convergent patterns of evolution of mitochondrial oxidative phosphorylation (OXPHOS) genes in electric fishes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
- The complete mitochondrial genome of a cold seep gastropod Phymorhynchus buccinoides (Neogastropoda: Conoidea: Raphitomidae).PloS one · 2020Article
- The complete mitogenome ofPeerJ · 2020Article
- Divergence history and hydrothermal vent adaptation of decapod crustaceans: A mitogenomic perspective.PloS one · 2019Article
- Article
- Mitochondrial DNA and temperature tolerance in lager yeasts.Science advances · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mechanism of oxidative phosphorylation is well understood, but evolution of the proteins involved is not. We combined phylogenetic, genomic, and structural biology analyses to examine the evolution of twelve mitochondrial encoded proteins of closely related, yet phenotypically diverse, Pacific salmon. Two separate analyses identified the same seven positively selected sites in ND5. A strong signal was also detected at three sites of ND2. An energetic coupling analysis revealed several structures in the ND5 protein that may have co-evolved with the selected sites. These data implicate Complex I, specifically the piston arm of ND5 where it connects the proton pumps, as important in the evolution of Pacific salmon. Lastly, the lineage to Chinook experienced rapid evolution at the piston arm.
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