ReviewClinical & developmental immunology2012
Current concepts of immunology and diagnosis in amniotic fluid embolism.
Review in Clinical & developmental immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 101 citations in OpenAlex.
- Intraoperative Collapse During First-Trimester Abortion: Hyperleukocytosis Crisis, Thrombotic Pulmonary Embolism, or Amniotic Fluid Embolism?International journal of women's health · 2026Article
- Perioperative management of critical obstetric hemorrhage after cesarean delivery in a patient with hereditary hemorrhagic telangiectasia: a case report.JA clinical reports · 2025Article
- [Cell salvage in obstetrics-Background and practical implementation].Die Anaesthesiologie · 2024Review
- Article
- Shock-Associated Systemic Inflammation in Amniotic Fluid Embolism, Complicated by Clinical Death.Pathophysiology : the official journal of the International Society for Pathophysiology · 2023Article
- Amniotic fluid embolism causing multiorgan embolisms and reinforces the need for point-of-care ultrasound.Qatar medical journal · 2023Article
- Fibrinogen may aid in the early differentiation between amniotic fluid embolism and postpartum haemorrhage: a retrospective chart review.Scientific reports · 2021Article
- Maternal death analysis based on data from the nationwide registration system in Japan (2010-2018).Pathology international · 2021Review
- Disseminated intravascular coagulation type of amniotic fluid embolism: a challenging case report with favorable outcome.The Pan African medical journal · 2021Article
- Amniotic fluid embolism: A rare cause of maternal collapse-A case report.Clinical case reports · 2020Article
- Non-thrombotic pulmonary embolism in emergency CT.Emergency radiology · 2020Review
- A case of amniotic fluid embolism successfully treated by multidisciplinary treatment.JA clinical reports · 2019Article
- Amniotic Fluid Embolism Treated with Veno-Arterial Extracorporeal Membrane Oxygenation.Case reports in critical care · 2019Article
- Amniotic fluid embolism.BJA education · 2018Review
- Amniotic Fluid Embolism. Is a New Pregnancy Possible? Case Report.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2017Article
- Amniotic fluid embolism: an Australian-New Zealand population-based study.BMC pregnancy and childbirth · 2015Article
- Therapeutic application of C1 esterase inhibitor concentrate for clinical amniotic fluid embolism: a case report.Clinical case reports · 2015Article
- Protein S deficiency present in a pregnant woman with dyspnea, abdominal pains, restlessness, agitation and hypofibrinogenemia.Clinical case reports · 2015Article
- Amniotic fluid embolism pathophysiology suggests the new diagnostic armamentarium: β-tryptase and complement fractions C3-C4 are the indispensable working tools.International journal of molecular sciences · 2015Review
- Amniotic Fluid Embolism (AFE) in China: Are maternal mortality and morbidity preventable?Intractable & rare diseases research · 2014Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amniotic fluid embolism (AFE) is one of the leading causes of maternal mortality and morbidity in developed countries. Current thinking about pathophysiology has shifted away from embolism toward a maternal immune response to the fetus. Two immunologic mechanisms have been studied to date. Anaphylaxis appears to be doubtful while the available evidence supports a role for complement activation. With the mechanism remaining to be elucidated, AFE remains a clinical diagnosis. It is diagnosed based on one or more of four key signs/symptoms: cardiovascular collapse, respiratory distress, coagulopathy, and/or coma/seizures. The only laboratory test that reliably supports the diagnosis is the finding of fetal material in the maternal pulmonary circulation at autopsy. Perhaps the most compelling mystery surrounding AFE is not why one in 20,000 parturients are afflicted, but rather how the vast majority of women can tolerate the foreign antigenic presence of their fetus both within their uterus and circulation?
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.