Evidence map›Paper›PMID 21967760›Full record

ArticleBioinformatics (Oxford, England)2011

ProfileChaser: searching microarray repositories based on genome-wide patterns of differential expression.

Jesse M Engreitz, Rong Chen, Alexander A Morgan, Joel T Dudley, Rohan Mallelwar, Atul J Butte

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Vitamin D Receptor Signaling and Cancer.Endocrinology and metabolism clinics of North America · 2017
    Review
  8. A question of fate.PLoS biology · 2017
    Article
  9. EMPOWERING MULTI-COHORT GENE EXPRESSION ANALYSIS TO INCREASE REPRODUCIBILITY.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2017
    Article
  10. Article
  11. Article
  12. Vitamin D receptor and RXR in the post-genomic era.Journal of cellular physiology · 2015
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jesse M EngreitzDivision of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA.
Rong Chen
Alexander A Morgan
Joel T Dudley
Rohan Mallelwar
Atul J Butte

Funding

POSTDOCTORAL TRAINING IN MEDICAL INFORMATION SCIENCEST15LM007033 · NLM · STANFORD UNIVERSITY · PI SYLVIA KATINA PLEVRITIS · 1985 to 2026
$25.5M
Integrating Microarray and Proteomic Data by Ontology-based AnnotationR01LM009719 · NLM · STANFORD UNIVERSITY · PI BUTTE, ATUL J · 2008 to 2011
$1.1M
Howard Hughes Medical InstituteNLM NIH HHS R01 LM009719NLM NIH HHS T15 LM007033
6 · The paper itself

Abstract

summaryWe introduce ProfileChaser, a web server that allows for querying the Gene Expression Omnibus based on genome-wide patterns of differential expression. Using a novel, content-based approach, ProfileChaser retrieves expression profiles that match the differentially regulated transcriptional programs in a user-supplied experiment. This analysis identifies statistical links to similar expression experiments from the vast array of publicly available data on diseases, drugs, phenotypes and other experimental conditions. AVAILABILITY: http://profilechaser.stanford.edu CONTACT: abutte@stanford.edu SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Indexed as

Gene Expression ProfilingInternetOligonucleotide Array Sequence AnalysisAnimalsBreast NeoplasmsCell Line, TumorDatabases, GeneticFemaleForkhead Box Protein O3Forkhead Transcription FactorsGenome-Wide Association StudyHumansMaleProstatic NeoplasmsReceptors, EstrogenUser-Computer InterfaceForkhead Box Protein O3Forkhead Transcription FactorsFoxO3 protein, mouseReceptors, Estrogen

Identifiers

PMID21967760
PMCPMC3223361

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.