ArticleJournal of women's health (2002)2012
Heart rate variability and exercise in aging women.
Article in Journal of women's health (2002), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Exercise Frequency Determines Heart Rate Variability Gains in Older People: A Meta-Analysis and Meta-Regression.Sports medicine (Auckland, N.Z.) · 2019Pooled it
- Supramaximal high-intensity interval training improves heart rate variability in older adults: A randomized controlled trial.Physiological reports · 2026Trial
- Heart Rate Variability and Cardiovascular Fitness: What We Know so Far.Vascular health and risk management · 2021Review
- Heart Rate Variability Mainly Relates to Cognitive Executive Functions and Improves Through Exergame Training in Older Adults: A Secondary Analysis of a 6-Month Randomized Controlled Trial.Frontiers in aging neuroscience · 2020Article
- Impact of functional training on geometric indices and fractal correlation property of heart rate variability in postmenopausal women.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2018Article
- Autonomic Nervous System and Stress to Predict Secondary Ischemic Events after Transient Ischemic Attack or Minor Stroke: Possible Implications of Heart Rate Variability.Frontiers in neurology · 2018Article
- Higher vagal activity as related to survival in patients with advanced breast cancer: an analysis of autonomic dysregulation.Psychosomatic medicine · 2015Article
- Diabetes and technology for increased activity study: the effects of exercise and technology on heart rate variability and metabolic syndrome risk factors.Frontiers in endocrinology · 2013Article
- Neural reflexes in inflammation and immunity.The Journal of experimental medicine · 2012Review
- Exercise and the cardiovascular system.Cardiology research and practice · 2012Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
backgroundOur group has shown a positive dose-response in maximal cardiorespiratory exercise capacity (VO(2max)) and heart rate variability (HRV) to 6 months of exercise training but no improvement in VO(2max) for women ≥60 years. Here, we examine the HRV response to exercise training in postmenopausal women younger and older than 60 years.
methodsWe examined 365 sedentary, overweight, hypertensive, postmenopausal women randomly assigned to sedentary control or exercise groups exercising at 50% (4 kcal/kg/week, [KKW]), 100% (8 KKW) and 150% (12 KKW) of the National Institutes of Health (NIH) Consensus Development Panel physical activity guidelines. Primary outcomes included time and frequency domain indices of HRV.
resultsOverall, our analysis demonstrated a significant improvement in parasympathetic tone (rMSSD and high frequency power) for both age strata at 8 KKW and 12 KKW. For rMSSD, the age-stratified responses were: control, <60 years, 0.20 ms, 95% confidence interval (CI)-2.40, 2.81; ≥60 years, 0.07 ms, 95% CI -3.64, 3.79; 4 KKW, <60 years, 3.67 ms, 95% CI 1.55, 5.79; ≥60 years, 1.20 ms, 95% CI -1.82, 4.22; 8-KKW, <60 years, 3.61 ms, 95% CI 0.88, 6.34; ≥60 years, 5.75 ms, 95% CI 1.89, 9.61; and 12-KKW, <60 years, 5.07 ms, 95% CI 2.53, 7.60; ≥60 years, 4.28 ms, 95% CI 0.42, 8.14.
conclusionsVO(2max) and HRV are independent risk factors for cardiovascular disease (CVD) mortality. Despite no improvement in VO(2max), parasympathetic indices of HRV increased in women ≥60 years. This is clinically important, as HRV has important CVD risk and neurovisceral implications beyond cardiorespiratory function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.