Evidence map›Paper›PMID 21966248›Full record

ArticleCurrent genomics2011

Induction and transcriptional regulation of laccases in fungi.

Alessandra Piscitelli, Paola Giardina, Vincenzo Lettera, Cinzia Pezzella, Giovanni Sannia, Vincenza Faraco

Open access · bronzeAbstract read
In one paragraph

Article in Current genomics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed
22.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 321 citations in OpenAlex.

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  11. A food color based colorimetric assay forbioRxiv : the preprint server for biology · 2024
    Article
  12. Article
  13. Copper increases laccase gene transcription and extracellular laccase activity in Pleurotus eryngii KS004.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  14. Article
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  16. Review
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  19. Silencing of the Laccase (International journal of molecular sciences · 2023
    Article
  20. Article

44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alessandra PiscitelliUniversity of Naples "Federico II", Dipartimento di Chimica Organica e Biochimica, Complesso Universitario Monte S. Angelo, via Cintia 4, 80126 Napoli, Italy.
Paola Giardina
Vincenzo Lettera
Cinzia Pezzella
Giovanni Sannia
Vincenza Faraco
University of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal laccases are phenol oxidases widely studied for their use in several industrial applications, including pulp bleaching in paper industry, dye decolourisation, detoxification of environmental pollutants and revalorization of wastes and wastewaters. The main difficulty in using these enzymes at industrial scale ensues from their production costs. Elucidation of the components and the mechanisms involved in regulation of laccase gene expression is crucial for increasing the productivity of native laccases in fungi. Laccase gene transcription is regulated by metal ions, various aromatic compounds related to lignin or lignin derivatives, nitrogen and carbon sources. In this manuscript, most of the published results on fungal laccase induction, as well as analyses of both the sequences and putative functions of laccase gene promoters are reviewed. Analyses of promoter sequences allow defining a correlation between the observed regulatory effects on laccase gene transcription and the presence of specific responsive elements, and postulating, in some cases, a mechanism for their functioning. Only few reports have investigated the molecular mechanisms underlying laccase regulation by different stimuli. The reported analyses suggest the existence of a complex picture of laccase regulation phenomena acting through a variety of cis acting elements. However, the general mechanisms for laccase transcriptional regulation are far from being unravelled yet.

Indexed as

ACE1aromatic compoundscopperMREnitrogenpromoterXRE.

Identifiers

PMID21966248
PMCPMC3129044
OpenAlexW1982475797

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.