Evidence map›Paper›PMID 21966198›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2011

Outcome of penetrating keratoplasty in corneal ulcer: a single-center experience.

Mohammad Reza Sedghipour, Rana Sorkhabi, Abdollah Shenasi, Hassan Dehghan

Open access · goldAbstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Collagen cross-linking for resistant corneal ulcer.International ophthalmology · 2013
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  14. Non-antibiotic management of bacterial keratitis.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mohammad Reza SedghipourDepartment of Ophthalmology, Tabriz University of Medical Sciences, Tabriz, Iran.
Rana Sorkhabi
Abdollah Shenasi
Hassan Dehghan
Tabriz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCorneal ulcers often lead to scarring and astigmatism, and significant loss of vision is a common consequence.

objectiveTo determine the rate of graft rejection, one of the most serious concerns with this procedure, and to evaluate the recovery of visual function in those patients for whom the operation was successful.

methodsWe describe a retrospective study of 33 corneal ulcer patients undergoing penetrating keratoplasty (PK) at the Tabriz Nikookari Eye Hospital.

resultsMean age of the patients was 44 ± 14 years. Most common risk factors for active keratitis were trauma, dry eye, and malnutrition. Culture-positive results included bacterial keratitis (n = 15) and fungal keratitis (n = 5). Perforation was a significant risk factor for therapeutic failure (P < 0.05). Age or gender had no statistically significant effects on the PK outcome (P > 0.05). Postoperative visual acuity had a significant association with preoperative visual acuity (P < 0.01). Graft rejection rate (27.2%) was similar to that reported in the literature.

conclusionAlthough lamellar keratoplasty has recently been established, there are practical reasons for continuing the use of PK in centers such as ours, with due attention to the requirement for topical immunosuppression to diminish the rate of graft rejection and antimicrobial treatment to prevent postoperative infection.

Indexed as

graft rejectionkeratitisperforationulcerative

Identifiers

PMID21966198
PMCPMC3180495
OpenAlexW2065150426

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.