ArticleJournal of parasitic diseases : official organ of the Indian Society for Parasitology2010
Potentilla fulgens (Family Rosaceae), a medicinal plant of north-east India: a natural anthelmintic?
Article in Journal of parasitic diseases : official organ of the Indian Society for Parasitology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Article
- Doktor Kot, Doktor Sla - book doctors, plant doctors and the segmentation of the medical market place in Meghalaya, northeast India.Anthropology & medicine · 2019Article
- Traditional Herbal Knowledge among the Inhabitants: A Case Study in Urgam Valley of Chamoli Garhwal, Uttarakhand, India.Evidence-based complementary and alternative medicine : eCAM · 2019Article
- Genistein: is the multifarious botanical a natural anthelmintic too?Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2018Article
- Cytotoxic and Enzyme Inhibitory Potential of TwoFrontiers in pharmacology · 2017Article
- Anthelmintic potential ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2016Article
- Is 'mainstreaming AYUSH' the right policy for Meghalaya, northeast India?BMC complementary and alternative medicine · 2015Article
- Evaluation of safety and protective effects of Potentilla fulgens root extract in experimentally induced diarrhea in mice.Journal of intercultural ethnopharmacologyArticle
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4 authors.
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Abstract
The cestode parasite, Raillietina echinobothrida and the trematode, Gastrothylax crumenifer were exposed to the ethanolic root peel extract of Potentilla fulgens, an antiparasitic local medicinal plant of Meghalaya, India, to evaluate the anthelmintic efficacy of the plant. The parasites were incubated in 1, 5, 10, 20, 50 and 100 mg crude alcoholic extract per ml of phosphate buffered saline (PBS) at a temperature of 37 ± 1°C. Paralysis and death were observed at 2.00 ± 0.05 and 2.80 ± 0.06 h for the cestode and 1.21 ± 0.06 and 2.18 ± 0.04 h for the trematode parasites at the highest test concentration of the plant extract. The commercial anthelmintic, Praziquantel (PZQ) showed higher activity at the tested concentration (0.02 mg/ml). To further investigate the efficacy of the plant extract, vital tegumental enzymes of the parasite viz. Acid phosphatase (AcPase), Alkaline phosphatase (AlkPase) and Adenosine triphosphatase (ATPase) were studied. Quantitatively, the total enzyme activity of AcPase, AlkPase and ATPase was found to be reduced significantly by 69.20, 66.43 and 29.63% for R. echinobothrida and 47.96, 51.79 and 42.63% for G. crumenifer, respectively compared to the respective controls; histochemical study also showed reduction in the visible staining of the enzymes. The reference drug, PZQ also showed more or less similar effect like that of the plant extract. The result suggests that phytochemicals of P. fulgens have anthelmintic potential.
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