Evidence map›Paper›PMID 21964975›Full record

Trial reportAIDS and behavior2012

Longitudinal effects of SafeTalk, a motivational interviewing-based program to improve safer sex practices among people living with HIV/AIDS.

Carol E Golin, Jo Anne Earp, Catherine A Grodensky, Shilpa N Patel, Chirayath Suchindran, Megha Parikh, Seth Kalichman, Kristine Patterson, Heidi Swygard, E Byrd Quinlivan and 3 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS and behavior, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Motivational interviewing for improving outcomes in youth living with HIV.The Cochrane database of systematic reviews · 2012
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  5. Guideline
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  17. Psychosocial Phenotype and Risky Sexual Behavior Among People Living with HIV in Changsha: A Latent Profile Analysis.International journal of sexual health : official journal of the World Association for Sexual Health · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Carol E GolinDivision of General Medicine and Clinical Epidemiology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Carol_Golin@unc.edu
Jo Anne Earp
Catherine A Grodensky
Shilpa N Patel
Chirayath Suchindran
Megha Parikh
Seth Kalichman
Kristine Patterson
Heidi Swygard
E Byrd Quinlivan
Kemi Amola
Zulfiya Chariyeva
Jennifer Groves

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SUSAN M. SMITH · 1999 to 2026
$31.6M
Carolina Population CenterR24HD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORGAN, SAMUEL PHILIP · 2005 to 2014
$10.0M
Promoting Safer Sex among Viremic HIV+ PatientsR01MH069989 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GOLIN, CAROL E · 2005 to 2008
$2.5M
Mentoring Junior Investigators: Comprehensive HIV PreventionK24HD069204 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GOLIN, CAROL E · 2013 to 2017
$789k
NIAID NIH HHS AI50410NIAID NIH HHS P30 AI050410NICHD NIH HHS K24 HD069204NICHD NIH HHS R24 HD050924NIDDK NIH HHS DK56350NIDDK NIH HHS P30 DK056350NIMH NIH HHS R01 MH069989NIMH NIH HHS R01-MH069989
6 · The paper itself

Abstract

Programs to help people living with HIV/AIDS practice safer sex are needed to prevent transmission of HIV and other sexually transmitted infections. We sought to assess the impact of SafeTalk, a multicomponent motivational interviewing-based safer sex program, on HIV-infected patients' risky sexual behavior. We enrolled sexually active adult HIV-infected patients from one of three clinical sites in North Carolina and randomized them to receive the 4-session SafeTalk intervention versus a hearthealthy attention-control. There was no significant difference in the proportion of people having unprotected sex between the two arms at enrollment. SafeTalk significantly reduced the number of unprotected sex acts with at-risk partners from baseline, while in controls the number of unprotected sex acts increased. Motivational interviewing can provide an effective, flexible prevention intervention for a heterogeneous group of people living with HIV.

Indexed as

Acquired Immunodeficiency SyndromeAdultDirective CounselingFemaleFocus GroupsHealth Knowledge, Attitudes, PracticeHumansLongitudinal StudiesMaleMotivationNorth CarolinaProgram EvaluationSexual BehaviorSexual PartnersSurveys and QuestionnairesTreatment Outcome

Identifiers

PMID21964975
PMCPMC3670095

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.