ArticleDie Naturwissenschaften2011
Promiscuity in mice is associated with increased vaginal bacterial diversity.
Article in Die Naturwissenschaften, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 25 citations in OpenAlex.
- Integrating the Microbiome Into Infection Ecology and Evolution in Wild Animals.Molecular ecology · 2026Review
- Testing for Functional Adaptation in a Genital Bone: Baculum Size, Shape, and Microstructure Show Little Plastic Response to Mating Across Five Rodent Species.Integrative organismal biology (Oxford, England) · 2026Article
- Microbial, proteomic, and metabolomic profiling of the estrous cycle in wild house mice.Microbiology spectrum · 2024Article
- Social complexity as a driving force of gut microbiota exchange among conspecific hosts in non-human primates.Frontiers in integrative neuroscience · 2022Review
- Interactions between reproductive biology and microbiomes in wild animal species.Animal microbiome · 2021Review
- Bacterial community dynamics during embryonic development of the little skate (Leucoraja erinacea).Animal microbiome · 2021Article
- Oral and vaginal microbiota in selected field mice of the genus Apodemus: a wild population study.Scientific reports · 2020Article
- Mating system is correlated with immunogenetic diversity in sympatric species of Peromyscine mice.PloS one · 2020Article
- ANCHOR: a 16S rRNA gene amplicon pipeline for microbial analysis of multiple environmental samples.Environmental microbiology · 2019Article
- Differential gene expression in relation to mating system in Peromyscine rodents.Ecology and evolution · 2019Article
- Differential sexual network connectivity offers a parsimonious explanation for population-level variations in the prevalence of bacterial vaginosis: a data-driven, model-supported hypothesis.BMC women's health · 2019Article
- The Cloacal Microbiome Changes with the Breeding Season in a Wild Bird.Integrative organismal biology (Oxford, England) · 2019Article
- Peromyscus transcriptomics: Understanding adaptation and gene expression plasticity within and between species of deer mice.Seminars in cell & developmental biology · 2017Review
- Primate vaginal microbiomes exhibit species specificity without universal Lactobacillus dominance.The ISME journal · 2014Article
- Is promiscuity associated with enhanced selection on MHC-DQα in mice (genus Peromyscus)?PloS one · 2012Article
- Genomic analysis of MHC-based mate choice in the monogamous California mouse.Behavioral ecology : official journal of the International Society for Behavioral EcologyArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Differences in the number of sexual partners (i.e., mating system) have the potential to exert a strong influence on the bacterial communities present in reproductive structures like the vagina. Because this structure serves as a conduit for gametes, bacteria present there may have a pronounced, direct effect on host reproductive success. As a first step towards the identification of the relationship between sexual behavior and potentially pathogenic bacterial communities inhabiting vital reproductive structures, as well as their potential effects on fitness, I sought to quantify differences in bacterial diversity in a promiscuous and monogamous mammal species. To accomplish this, I used two sympatric species of Peromyscus rodents--Peromyscus californicus and Peromyscus maniculatus that differ with regard to the number of sexual partners per individual to test the hypothesis that bacterial diversity should be greater in the promiscuous P. maniculatus relative to the monogamous P. californicus. As predicted, phylogenetically controlled and operational taxonomic unit-based indices of bacterial diversity indicated that diversity is greater in the promiscuous species. These results provide important new insights into the effects of mating system on bacterial diversity in free-living vertebrates, and may suggest a potential cost of promiscuity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.