ReviewCellular and molecular life sciences : CMLS2012
Propagation of histone marks and epigenetic memory during normal and interrupted DNA replication.
Review in Cellular and molecular life sciences : CMLS, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- RTEL1 is required for silencing and epigenome stability.Nucleic acids research · 2023Article
- Dysfunctional CAF-I reveals its role in cell cycle progression and differential regulation of gene silencing.Cell cycle (Georgetown, Tex.) · 2019Article
- Replication stress affects the fidelity of nucleosome-mediated epigenetic inheritance.PLoS genetics · 2017Article
- Forks on the Run: Can the Stalling of DNA Replication Promote Epigenetic Changes?Frontiers in genetics · 2017Review
- Chromatin determinants of the inner-centromere rely on replication factors with functions that impart cohesion.Oncotarget · 2016Article
- Maintaining Epigenetic Inheritance During DNA Replication in Plants.Frontiers in plant science · 2016Review
- Replication of Structured DNA and its implication in epigenetic stability.Frontiers in genetics · 2015Review
- Epigenetic memory in the context of nuclear reprogramming and cancer.Briefings in functional genomics · 2013Review
- The G4 genome.PLoS genetics · 2013Article
- Origins and formation of histone methylation across the human cell cycle.Molecular and cellular biology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Although all nucleated cells within a multicellular organism contain a complete copy of the genome, cell identity relies on the expression of a specific subset of genes. Therefore, when cells divide they must not only copy their genome to their daughters, but also ensure that the pattern of gene expression present before division is restored. While the carrier of this epigenetic memory has been a topic of much research and debate, post-translational modifications of histone proteins have emerged in the vanguard of candidates. In this paper we examine the mechanisms by which histone post-translational modifications are propagated through DNA replication and cell division, and we critically examine the evidence that they can also act as vectors of epigenetic memory. Finally, we consider ways in which epigenetic memory might be disrupted by interfering with the mechanisms of DNA replication.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.