ArticleObesity surgery2011
Effects of laparoscopic Roux-en-Y gastric bypass (LRYGB) on weight loss and biomarker parameters in morbidly obese patients: a 12-month follow-up.
Article in Obesity surgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of Metabolic and Bariatric Surgery on Serum Uric Acid and its Association with Renal Function, and Visceral Adiposity: A Systematic Review and Meta-Analysis.Obesity surgery · 2026Pooled it
- The impact of preoperative vitamin administration on skeletal status following sleeve gastrectomy in young and middle-aged women: a randomized controlled trial.International journal of obesity (2005) · 2021Trial
- Probiotics administration following sleeve gastrectomy surgery: a randomized double-blind trial.International journal of obesity (2005) · 2018Trial
- The Effects of One Anastomosis Gastric Bypass Surgery on the Gastrointestinal Tract.Nutrients · 2022Article
- Comparison of Laparoscopic Roux-en-Y Gastric Bypass and Laparoscopic Sleeve Gastrectomy on Weight Loss, Weight Regain, and Remission of Comorbidities: A 5 Years of Follow-up Study.Obesity surgery · 2020Article
- Article
- Obesity-related acetylcholinesterase elevation is reversed following laparoscopic sleeve gastrectomy.International journal of obesity (2005) · 2019Article
- The Effect of Pre-Surgery Information Online Lecture on Nutrition Knowledge and Anxiety Among Bariatric Surgery Candidates.Obesity surgery · 2018Article
- Comparison of Outcomes Between Laparoscopic Roux-en-Y Gastric Bypass and Sleeve Gastrectomy in a Lebanese Bariatric Surgical Practice.Obesity surgery · 2018Article
- Do Bariatric Patients Follow Dietary and Lifestyle Recommendations during the First Postoperative Year?Obesity surgery · 2017Article
- Poor Health Behaviors Prior to Laparoscopic Sleeve Gastrectomy Surgery.Obesity surgery · 2017Article
- Laparoscopic Adjustable Gastric Banded Plication (Lagbp): Standardization of Surgical Technique and Analysis of Surgical Outcomes.Obesity surgery · 2016Article
- Parathyroid Hormone Levels May Predict Nonalcoholic Steatohepatitis in Morbidly Obese Patients.Hepatitis monthly · 2015Article
- The effects of cystatin C and alkaline phosphatase changes on cognitive function 12-months after bariatric surgery.Journal of the neurological sciences · 2014Article
- Impact of obesity on liver function tests: is nonalcoholic fatty liver disease the only player? A review article.Porto biomedical journalReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLaparoscopic Roux-en-Y gastric bypass (LRYGB) is suggested as the gold standard of the surgical techniques for morbid obesity treatment. The aim of this study was to evaluate the weight loss and biomarker parameter changes over a 1-year period following LRYGB in Iranian morbidly obese patients.
methodsSixty patients who had undergone LRYGB from June 2006 to August 2008 were followed up. Complication rates and changes in anthropometric indices, metabolic parameters, and obesity-related comorbidities were evaluated.
resultsDuring the mean follow-up duration of 27.2 ± 9.4 months, the mean weight reduced from 128.8 ± 20.4 to 86.9 ± 12.7 kg with excess weight loss (%EWL) of 63.8 ± 15.6%. The male young-adolescent patients showed more weight loss than females. Biochemical parameter changes were reduction of fasting blood sugar by 19%, total cholesterol by 17%, triglyceride by 30%, low-density lipoprotein by 19%, aspartate aminotransferase by 44%, alanine aminotransferase by 52%, alkaline phosphatase by 33%, and uric acid by 19%, while high-density lipoprotein (HDL) levels increased by 22%. HDL level change was the only biomarker factor showing correlation with age (P = 0.005, r = -0.353, R(2) = 0.125). Obesity comorbidities were resolved considerably. There were two cases of surgical complications and no case of mortality.
conclusionLRYGB appears to be a safe and effective procedure with a low complication rate in Iranian morbidly obese patients. It results in weight loss, reduction in obesity comorbidities, increasing HDL, and decreasing other measured plasma biochemical parameters. Based on our results, we suggest that LRYGB would benefit young male morbidly obese patients more than others.
Indexed as
Identifiers
21964796What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.