Evidence map›Paper›PMID 21964186›Full record

ArticleThe American journal of pathology2011

The earliest tau dysfunction in Alzheimer's disease? Tau phosphorylated at s422 as a toxic seed.

Kellen Voss, John Koren, Chad A Dickey

Abstract readComment
In one paragraph

Article in The American journal of pathology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  8. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Kellen VossUSF Health Byrd Alzheimer's Institute, Department of Molecular Medicine, University of South Florida, Tampa, Florida, USA.
John Koren
Chad A Dickey

Funding

The Hsp90 cochaperone FKBP51 regulates tau structure and functionR01NS073899 · NINDS · UNIVERSITY OF SOUTH FLORIDA · PI Laura J Blair · 2011 to 2026
$6.9M
Chaperone-mediated signaling in Alzheimer's diseaseR00AG031291 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI DICKEY, CHAD A. · 2008 to 2010
$889k
NIA NIH HHS R00 AG031291NIA NIH HHS R00AG031291NINDS NIH HHS R01 NS073899NINDS NIH HHS R01NS073899
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer DiseaseCholinergic NeuronsCognitive DysfunctionFemaleHumansMaleProsencephalon

Identifiers

PMID21964186
PMCPMC3204013

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.