Evidence map›Paper›PMID 21964173›Full record

ArticleMayo Clinic proceedings2011

Ethnic differences in cardiovascular risks and mortality in atherothrombotic disease: insights from the Reduction of Atherothrombosis for Continued Health (REACH) registry.

Telly A Meadows, Deepak L Bhatt, Christopher P Cannon, Bernard J Gersh, Joachim Röther, Shinya Goto, Chiau-Suong Liau, Peter W F Wilson, Genevieve Salette, Sidney C Smith and 2 more

Open access · greenAbstract read
In one paragraph

Article in Mayo Clinic proceedings, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 4 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 4 syntheses or guidelines pooled it, 124 citations in OpenAlex.

  1. Pooled it
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  6. How Sex and Race/Ethnicity Influence Interventional Cardiology Outcomes: What Do We Know?Journal of the Society for Cardiovascular Angiography & Interventions · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 5 countries.

Telly A MeadowsMid Carolina Cardiology, Charlotte, NC, USA.
Deepak L Bhatt
Christopher P Cannon
Bernard J Gersh
Joachim Röther
Shinya Goto
Chiau-Suong Liau
Peter W F Wilson
Genevieve Salette
Sidney C Smith
Ph Gabriel Steg
REACH Registry Investigators
Brigham and Women's Hospital · USEmory University · USJohannes Wesling Klinikum Minden · DEMayo Clinic · USNational Taiwan University Hospital · TWSanofi (France) · FRTokai University · JPUniversité Paris Cité · FRUniversity of North Carolina at Chapel Hill · USVA Boston Healthcare System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine whether ethnic-specific differences in the prevalence of cardiovascular risk factors and outcomes exist worldwide among individuals with stable arterial disease. PATIENTS AND

methodsFrom December 1, 2003, to June 30, 2004, the prospective, observational REduction of Atherothrombosis for Continued Health (REACH) Registry enrolled 49,602 out-patients with coronary artery disease, cerebrovascular disease, and/or peripheral arterial disease from 7 predefined ethnic/racial groups: white, Hispanic, East Asian, South Asian, Other Asian, black, and Other (comprising any race distinct from those specified). The baseline demographic and risk factor profiles, medication use, and 2-year cardiovascular outcomes were assessed among these groups.

resultsThe prevalence of traditional atherothrombotic risk factors varied significantly among the ethnic/racial groups. The use of medical therapies to reduce risk was comparable among all groups. At 2-year follow-up, the rate of cardiovascular death was significantly higher in blacks (6.1%) compared with all other ethnic/racial groups (3.9%; P=.01). Cardiovascular death rates were significantly lower in all 3 Asian ethnic/racial groups (overall, 2.1%) compared with the other groups (4.5%; P<.001).

conclusionThe REACH Registry, a large international study of individuals with atherothrombotic disease, documents the important ethnic-specific differences in cardiovascular risk factors and variations in cardiovascular mortality that currently exist worldwide.

Indexed as

AdultAgedAtherosclerosisCardiovascular DiseasesFemaleHumansMaleMiddle AgedPrevalenceProspective StudiesRegistriesRisk AssessmentRisk FactorsVenous Thrombosis

Identifiers

PMID21964173
PMCPMC3184025
OpenAlexW2135488617

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.