Evidence map›Paper›PMID 21963522›Full record

ReviewDrug discovery today2011

Empowering industrial research with shared biomedical vocabularies.

Lee Harland, Christopher Larminie, Susanna-Assunta Sansone, Sorana Popa, M Scott Marshall, Michael Braxenthaler, Michael Cantor, Wendy Filsell, Mark J Forster, Enoch Huang and 8 more

Abstract readReview
In one paragraph

Review in Drug discovery today, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Lee HarlandConnected Discovery Ltd., London, UK. lee@connecteddiscovery.com
Christopher Larminie
Susanna-Assunta Sansone
Sorana Popa
M Scott Marshall
Michael Braxenthaler
Michael Cantor
Wendy Filsell
Mark J Forster
Enoch Huang
Andreas Matern
Mark Musen
Jasmin Saric
Ted Slater
Jabe Wilson
Nick Lynch
John Wise
Ian Dix

Funding

STANFORD COMPOSITE(RMI)U54HG004028 · NHGRI · STANFORD UNIVERSITY · PI MUSEN, MARK A · 2005 to 2014
$36.2M
Biotechnology and Biological Sciences Research Council BB/E025080/1Biotechnology and Biological Sciences Research Council BB/I000771/1NHGRI NIH HHS U54 HG004028
6 · The paper itself

Abstract

The life science industries (including pharmaceuticals, agrochemicals and consumer goods) are exploring new business models for research and development that focus on external partnerships. In parallel, there is a desire to make better use of data obtained from sources such as human clinical samples to inform and support early research programmes. Success in both areas depends upon the successful integration of heterogeneous data from multiple providers and scientific domains, something that is already a major challenge within the industry. This issue is exacerbated by the absence of agreed standards that unambiguously identify the entities, processes and observations within experimental results. In this article we highlight the risks to future productivity that are associated with incomplete biological and chemical vocabularies and suggest a new model to address this long-standing issue.

Indexed as

Terminology as TopicBiomedical ResearchCooperative BehaviorDatabases, FactualDrug DiscoveryDrug IndustryHumansVocabulary

Identifiers

PMID21963522
PMCPMC7098809

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.