Evidence map›Paper›PMID 21963333›Full record

ArticleDrug and alcohol dependence2012

Analyses related to the development of DSM-5 criteria for substance use related disorders: 2. Proposed DSM-5 criteria for alcohol, cannabis, cocaine and heroin disorders in 663 substance abuse patients.

Deborah S Hasin, Miriam C Fenton, Cheryl Beseler, Jung Yeon Park, Melanie M Wall

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 3 pooled it
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 3 syntheses or guidelines pooled it, 128 citations in OpenAlex.

  1. Pooled it
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  8. Pharmacokinetics-Informed Neural Network for Predicting Opioid Administration Moments with Wearable Sensors.Proceedings of the ... AAAI Conference on Artificial Intelligence. AAAI Conference on Artificial Intelligence · 2024
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  15. A neuroeconomic signature of opioid craving: How fluctuations in craving bias drug-related and nondrug-related value.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Deborah S HasinCollege of Physicians and Surgeons, Department of Psychiatry, Columbia University, New York, NY 10032, United States. dsh2@columbia.edu
Miriam C Fenton
Cheryl Beseler
Jung Yeon Park
Melanie M Wall
Columbia University · USNew York State Psychiatric Institute

Funding

Phenotypes for Drug Abuse:Epidemiologic-Genetic ApproachR01DA018652 · NIDA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI HASIN, DEBORAH S · 2004 to 2018
$5.3M
Adverse childhood experiences, personality psychopathology, and alcohol disordersU01AA018111 · NIAAA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI HASIN, DEBORAH S · 2009 to 2013
$3.4M
Epidemiologic Studies of Alcohol Use Disorders (ongoing)K05AA014223 · NIAAA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HASIN, DEBORAH S · 2003 to 2012
$1.5M
COURSE OF DRUG USE DISORDERS--EFFECTS OF COMORBIDITYR01DA008409 · NIDA · NEW YORK STATE PSYCHIATRIC INSTITUTE · PI HASIN, DEBORAH S. · 1994 to 1999
–
NIAAA NIH HHS K05 AA014223NIAAA NIH HHS K05AA014223NIAAA NIH HHS U01 AA018111NIAAA NIH HHS U01AA018111NIDA NIH HHS R01 DA018652NIDA NIH HHS R01DA018652NIDA NIH HHS R01DA08409
6 · The paper itself

Abstract

backgroundA number of changes have been proposed and investigated in the criteria for substance use disorders in DSM-5. However, although clinical utility of DSM-5 is a high priority, relatively little of the empirical evidence supporting the changes was obtained from samples of substance abuse patients.

methodsProposed changes were examined in 663 patients in treatment for substance use disorders, evaluated by experienced clinicians using the Psychiatric Research Interview for Substance and Mental Disorders (PRISM). Factor and item response theory analysis was used to investigate the dimensionality and psychometric properties of alcohol, cannabis, cocaine and heroin abuse and dependence criteria, and craving.

resultsThe seven dependence criteria, three of the abuse criteria (hazardous use; social/interpersonal problems related to use; neglect of roles to use), and craving form a unidimensional latent trait for alcohol, cannabis, cocaine and heroin. Craving did not add significantly to the total information offered by the dependence criteria, but adding the three abuse criteria and craving together did significantly increase total information for the criteria sets associated with alcohol, cannabis and heroin.

conclusionAmong adult patients in treatment for substance disorders, the alcohol, cannabis, cocaine and heroin criteria for dependence, abuse (with the exception of legal problems), and craving measure a single underlying dimension. Results support the proposal to combine abuse and dependence into a single diagnosis in the DSM-5, omitting legal problems. Mixed support was provided for the addition of craving as a new criterion, warranting future studies of this important construct in substance use disorders.

Indexed as

Diagnostic and Statistical Manual of Mental DisordersAdolescentAdultAlcohol-Related DisordersCocaine-Related DisordersFemaleHeroin DependenceHumansMaleMarijuana AbuseMiddle AgedPsychometricsReproducibility of Results

Identifiers

PMID21963333
PMCPMC3755770
OpenAlexW2078736301

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.