Evidence map›Paper›PMID 21962442›Full record

ReviewCurrent opinion in genetics & development2011

Optical Coherence Tomography for live imaging of mammalian development.

Irina V Larina, Kirill V Larin, Monica J Justice, Mary E Dickinson

Abstract readReview
In one paragraph

Review in Current opinion in genetics & development, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Mouse Cardiovascular Imaging.Current protocols · 2024
    Review
  2. Article
  3. Imaging Approaches and the Quantitative Analysis of Heart Development.Journal of cardiovascular development and disease · 2023
    Review
  4. Review
  5. Mouse embryo phenotyping with optical coherence tomography.Frontiers in cell and developmental biology · 2022
    Review
  6. Article
  7. Embryonic Mouse Cardiodynamic OCT Imaging.Journal of cardiovascular development and disease · 2020
    Review
  8. Review
  9. Review
  10. Optical coherence tomography forBiomedical optics express · 2019
    Article
  11. Influence of blood flow on cardiac development.Progress in biophysics and molecular biology · 2018
    Review
  12. Perspectives: MRI of angiogenesis.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2018
    Review
  13. Review
  14. Cardiovascular Imaging in Mice.Current protocols in mouse biology · 2016
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Irina V LarinaDepartment of Molecular Physiology and Biophysics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, United States. larina@bcm.edu
Kirill V Larin
Monica J Justice
Mary E Dickinson

Funding

Consortium for Broad Based Disease Phenotyping of Knockout MiceU54HG006348 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI BEAUDET, ARTHUR L., PAYLOR, RICHARD E · 2011 to 2015
$17.0M
Phenotyping embryonic mammalian heart function using OCTR01HL095586 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI DICKINSON, MARY E, LARIN, KIRILL V · 2009 to 2012
$1.7M
NHGRI NIH HHS U54 HG006348NHLBI NIH HHS R01 HL095586NHLBI NIH HHS R01HL095586
6 · The paper itself

Abstract

Understanding the nature and mechanism of congenital defects of the different organ systems in humans has heavily relied on the analysis of the corresponding mutant phenotypes in rodent models. Optical Coherence Tomography (OCT) has recently emerged as a powerful tool to study early embryonic development. This non-invasive optical methodology does not require labeling and allows visualization of embryonic tissues with single cell resolution. Here, we will discuss how OCT can be applied for structural imaging of early mouse and rat embryos in static culture, cardiodynamic and blood flow analysis, and in utero embryonic imaging at later stages of gestation, demonstrating how OCT can be used to assess structural and functional birth defects in mammalian models.

Indexed as

AnimalsEmbryo, MammalianHumansImaging, Three-DimensionalTomography, Optical Coherence

Identifiers

PMID21962442
PMCPMC3208256

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.