Evidence map›Paper›PMID 21962422›Full record

Trial reportJournal of cardiac failure2011

Nurse-Enhanced Memory Intervention in Heart Failure: the MEMOIR study.

Susan J Pressler, Barbara Therrien, Penny L Riley, Cheng-Chen Chou, David L Ronis, Todd M Koelling, Dean G Smith, Barbara Jean Sullivan, Ann-Marie Frankini, Bruno Giordani

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of cardiac failure, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. A multidomain trial for cognition in women with cardiovascular disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Trial
  2. Trial
  3. Trial
  4. Trial
  5. Evidence-Based Heart Failure Medications and Cognition.The Journal of cardiovascular nursing
    Trial
  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Article
  11. Review
  12. Exercise and Cognitive Training Intervention Improves Self-Care, Quality of Life and Functional Capacity in Persons With Heart Failure.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2022
    Article
  13. Article
  14. Article
  15. Exercise and Cognitive Training as a Strategy to Improve Neurocognitive Outcomes in Heart Failure: A Pilot Study.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2019
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Susan J PresslerUniversity of Michigan School of Nursing, Ann Arbor, Michigan 48109, USA. spressle@umich.edu
Barbara Therrien
Penny L Riley
Cheng-Chen Chou
David L Ronis
Todd M Koelling
Dean G Smith
Barbara Jean Sullivan
Ann-Marie Frankini
Bruno Giordani

Funding

Translation and Dissemination CoreP30NR009000 · NINR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SAMPSELLE, CAROLYN M · 2005 to 2009
$2.1M
The Role of Cognitive Deficits in Chronic Heart FailureR01NR008147 · NINR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PRESSLER, SUSAN J · 2004 to 2007
$1.1M
NINR NIH HHS P30 NR009000NINR NIH HHS R01 NR008147
6 · The paper itself

Abstract

backgroundMany patients with heart failure (HF) have cognitive deficits, including memory loss.

objectivesThe aim of this study was to evaluate the efficacy of a cognitive training intervention on memory (primary outcome), working memory, psychomotor speed, executive function, and performance of cognitive activities and instrumental activities of daily living (IADLs). METHODS AND

resultsForty patients with HF were randomly assigned to the computerized plasticity-based cognitive training intervention called Brain Fitness or to the health education active control intervention. Advanced practice nurses made weekly home visits to assess symptoms and monitor intervention adherence. Patients completed demographic and clinical data (baseline), neuropsychologic tests (baseline and 8 and 12 weeks), and measures of cognitive and IADLs performance (baseline and 12 weeks) and satisfaction (12 weeks). Linear mixed models analyses indicated a significant group by time interaction for delayed recall memory (P = .032) and a significant time effect for total (list learning) (P < .001) and delayed (P = .015) recall memory, psychomotor speed (P = .029), and performance of IADLs (P = .006). Intervention adherence and patient satisfaction were high.

conclusionsTo our knowledge, this was the first test of Brain Fitness in HF. Although it was a preliminary study with limitations, results support the need for a larger randomized controlled trial to determine whether the memory loss of HF is amenable to plasticity-based interventions.

Indexed as

Activities of Daily LivingHealth EducationCognition DisordersFemaleHeart FailureHumansMaleMiddle AgedNeuropsychological TestsNursing ProcessTreatment Outcome

Identifiers

PMID21962422
PMCPMC3227743

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.