Evidence map›Paper›PMID 21961834›Full record

ArticleVeterinary research2011

PRNP genetic variability and molecular typing of natural goat scrapie isolates in a high number of infected flocks.

Eirini G Fragkiadaki, Gabriele Vaccari, Loukia V Ekateriniadou, Umberto Agrimi, Nektarios D Giadinis, Barbara Chiappini, Elena Esposito, Michela Conte, Romolo Nonno

Open access · goldAbstract read
In one paragraph

Article in Veterinary research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
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  7. Polymorphisms of Codons 110, 146, 211 and 222 at the GoatAnimals : an open access journal from MDPI · 2021
    Article
  8. Genetic Variation in the Prion Protein Gene (Animals : an open access journal from MDPI · 2021
    Article
  9. Animals : an open access journal from MDPI · 2021
    Article
  10. Novel Polymorphisms and Genetic Characteristics of the Prion Protein Gene (International journal of molecular sciences · 2020
    Article
  11. PRNP gene polymorphisms in main indigenous Turkish goat breeds.Tropical animal health and production · 2020
    Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Eirini G FragkiadakiNational Agricultural Research Foundation, Veterinary Research Institute, Thessaloniki, Greece. eirfrag@gmail.com.
Gabriele Vaccari
Loukia V Ekateriniadou
Umberto Agrimi
Nektarios D Giadinis
Barbara Chiappini
Elena Esposito
Michela Conte
Romolo Nonno
Istituto Superiore di Sanità · ITNational Agricultural Research Foundation · GRAristotle University of Thessaloniki · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One hundred and four scrapie positive and 77 negative goats from 34 Greek mixed flocks were analysed by prion protein gene sequencing and 17 caprine scrapie isolates from 11 flocks were submitted to molecular isolate typing. For the first time, the protective S146 variant was reported in Greece, while the protective K222 variant was detected in negative but also in five scrapie positive goats from heavily infected flocks. By immunoblotting six isolates, including two goat flockmates carrying the K222 variant, showed molecular features slightly different from all other Greek and Italian isolates co-analysed, possibly suggesting the presence of different scrapie strains in Greece.

Indexed as

AnimalsBlotting, WesternGenotyping TechniquesGoat DiseasesGoatsMolecular Sequence DataMolecular TypingPrionsScrapieSequence Analysis, ProteinPrions

Identifiers

PMID21961834
PMCPMC3190342
OpenAlexW2129469274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.