ArticleGastroenterology & hepatology2007
Small intestinal bacterial overgrowth: a comprehensive review.
Article in Gastroenterology & hepatology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04501380 (A Randomized Open Label Trial Evaluating the Efficacy of AEMCOLO), which is not on this map. Cited by 167 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Open Label Trial Evaluating the Efficacy of AEMCOLO (Rifamycin SV MMX) in the Treatment of Small Intestinal Bacterial Overgrowth (SIBO)
Who cites it
167 citing papers in PubMed, 9 syntheses or guidelines pooled it, 322 citations in OpenAlex.
- Prevalence of Liver Dysfunction After One-Anastomosis Gastric Bypass: A Systematic Review and Single-Arm Meta-analysis.Obesity surgery · 2025Pooled it
- Probiotics and gastrointestinal disorders: an umbrella meta-analysis of therapeutic efficacy.European journal of medical research · 2025Pooled it
- Show Me What You Have Inside-The Complex Interplay between SIBO and Multiple Medical Conditions-A Systematic Review.Nutrients · 2022Pooled it
- Obesity and Risk of Small Intestine Bacterial Overgrowth: A Systematic Review and Meta-Analysis.Digestive diseases and sciences · 2020Pooled it
- Pooled it
- Guideline
- Environmental enteric dysfunction pathways and child stunting: A systematic review.PLoS neglected tropical diseases · 2018Pooled it
- Meta-analysis: antibiotic therapy for small intestinal bacterial overgrowth.Alimentary pharmacology & therapeutics · 2013Pooled it
- Meta-analysis of oro-cecal transit time in fasting subjects.Pharmaceutical research · 2013Pooled it
- The Short-Term Effects and Tolerability of Low-Viscosity Soluble Fibre on Gastroparesis Patients: A Pilot Clinical Intervention Study.Nutrients · 2021Trial
- Trial
- Small Intestinal Bacterial Overgrowth Following Gastrointestinal Cancer Surgery: Current Evidence and Future Perspectives.Annals of gastroenterological surgery · 2026Review
- Article
- Evaluating the Risk ofJournal of clinical medicine · 2026Article
- Unraveling the Complexities of Small Intestinal Bacterial Overgrowth.Medicina (Kaunas, Lithuania) · 2026Review
- Beyond acid suppression: the multifaceted role of proton pump inhibitors inFrontiers in microbiology · 2026Review
- BiombalanceAntioxidants (Basel, Switzerland) · 2025Article
- Article
- Hydrogen Sulfide and Methane on Breath Test Correlate with Human Small Intestinal Hydrogen Sulfide Producers and Methanogens.Digestive diseases and sciences · 2025Article
- Guardians in the Gut: Mechanistic Insights into a Hidden Ally Against Triple-Negative Breast Cancer.Cancers · 2025Review
107 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Small intestinal bacterial overgrowth (SIBO), defined as excessive bacteria in the small intestine, remains a poorly understood disease. Initially thought to occur in only a small number of patients, it is now apparent that this disorder is more prevalent than previously thought. Patients with SIBO vary in presentation, from being only mildly symptomatic to suffering from chronic diarrhea, weight loss, and malabsorption. A number of diagnostic tests are currently available, although the optimal treatment regimen remains elusive. Recently there has been renewed interest in SIBO and its putative association with irritable bowel syndrome. In this comprehensive review, we will discuss the epidemiology, pathogenesis, clinical manifestations, diagnosis, and treatment of SIBO.
Indexed as
Identifiers
21960820PMC3099351W14708387What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.