Evidence map›Paper›PMID 21960714›Full record

ReviewClinical infectious diseases : an official publication of the Infectious Diseases Society of America2011

Tuberculosis of the central nervous system in immunocompromised patients: HIV infection and solid organ transplant recipients.

Christina A Nelson, Joseph R Zunt

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Brain Abscesses in the Tropics.Current tropical medicine reports · 2023
    Article
  7. Review
  8. Article
  9. Immunosuppressive Agents and Infectious Risk in Transplantation: Managing the "Net State of Immunosuppression".Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Review
  10. [Cauda equina syndrome in HIV patient].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2021
    Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. [Intracranial tuberculomas in Nouakchott, Mauritania].The Pan African medical journal · 2018
    Article
  18. Article
  19. Tuberculosis Meningitis.Current infectious disease reports · 2017
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Christina A NelsonDepartment of Neurology, Global Health, Medicine, and Epidemiology, University of Washington School of Medicine, Seattle, Washington, USA.
Joseph R Zunt
University of Washington · US

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Grace C. John-Stewart · 1988 to 2026
$104.9M
Fogarty International Clinical Research Scholars Support Center @ Vanderbilt-AAMCR24TW007988 · FIC · VANDERBILT UNIVERSITY · PI VERMUND, STEN H. · 2007 to 2011
$27.6M
Retrovial Infections of the Nervous System in PeruR01NS055627 · NINDS · UNIVERSITY OF WASHINGTON · PI ZUNT, JOSEPH RAYMOND · 2006 to 2010
$3.0M
FIC NIH HHS R24 TW007988NIAID NIH HHS P30 AI027757NINDS NIH HHS R01 NS055627NINDS NIH HHS R01NS55627
6 · The paper itself

Abstract

Central nervous system (CNS) tuberculosis (TB) is a devastating infection with high rates of morbidity and mortality worldwide and may manifest as meningitis, tuberculoma, abscess, or other forms of disease. Immunosuppression, due to either human immunodeficiency virus infection or solid organ transplantation, increases susceptibility for acquiring or reactivating TB and complicates the management of underlying immunosuppression and CNS TB infection. This article reviews how immunosuppression alters the clinical presentation, diagnosis, treatment, and outcome of TB infections of the CNS.

Indexed as

Immunocompromised HostCentral Nervous System DiseasesHIV InfectionsHumansOrgan TransplantationTreatment OutcomeTuberculosis

Identifiers

PMID21960714
PMCPMC3218626
OpenAlexW2157616426

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.