ArticleInflammation research : official journal of the European Histamine Research Society ... [et al.]2012
Seasonal changes in activities of human neutrophils in vitro.
Article in Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 39 citations in OpenAlex.
- Does seasonal variation affect the neuroimmune system? A retrospective [Neuroscience letters · 2024Article
- Neutrophil Functional Heterogeneity and Implications for Viral Infections and Treatments.Cells · 2022Review
- The contribution of sleep to the neuroendocrine regulation of rhythms in human leukocyte traffic.Seminars in immunopathology · 2022Review
- Seasonal and daytime variation in multiple immune parameters in humans: Evidence from 329,261 participants of the UK Biobank cohort.iScience · 2021Article
- The Circadian Clock and Viral Infections.Journal of biological rhythms · 2021Review
- Seasonal variation in the internet searches for gout: an ecological study.Clinical rheumatology · 2019Observational
- In Search of 'Birth Month Genes': Using Existing Data Repositories to Locate Genes Underlying Birth Month-Disease Relationships.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2016Article
- Disrupted seasonal biology impacts health, food security and ecosystems.Proceedings. Biological sciences · 2015Review
- Pediatric anti-NMDA receptor encephalitis is seasonal.Annals of clinical and translational neurology · 2014Article
- Neutrophil heterogeneity in health and disease: a revitalized avenue in inflammation and immunity.Open biology · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
OBJECTIVE AND
designWe present a retrospective analysis of previously collected blood samples to determine whether the immune response of neutrophils depends on the season i.e., short versus long days, in which blood samples were collected.
methodsThe bactericidal activity and adhesive capacity of neutrophils, the production of reactive oxygen species (ROS), and CD11b/CD18 molecule expression level were investigated. The investigated neutrophils were divided into two groups based on the time of blood collection: the winter season with short days and the summer season with long days.
resultsWe found seasonal variation in measurements of all the analyzed functional responses of neutrophils to stimuli. The strongest adhesion, as well as maximum values of ROS production, was presented by neutrophils isolated from the summer group. The highest bactericidal activity of neutrophils was also observed in blood donors from summer group.
conclusionsThe magnitude of the immune functional activity of neutrophils varies with the season of the year and is decreased in winter.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.