ArticleDigestive diseases and sciences2012
Endoscopic management of duodenal adenomas in familial adenomatous polyposis--a single-center experience.
Article in Digestive diseases and sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06435533 (Cold Atmospheric Plasma for the Endoscopic Treatment of Duodenal Polyps in Patients With Familial Adenomatous Polyposis), which is not on this map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cold Atmospheric Plasma for the Endoscopic Treatment of Duodenal Polyps in Patients With Familial Adenomatous Polyposis
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Japanese society for cancer of the colon and rectum (JSCCR) guidelines 2024 for the clinical practice of hereditary colorectal cancer.International journal of clinical oncology · 2026Guideline
- Updated European guidelines for clinical management of familial adenomatous polyposis (FAP), MUTYH-associated polyposis (MAP), gastric adenocarcinoma, proximal polyposis of the stomach (GAPPS) and other rare adenomatous polyposis syndromes: a joint EHTG-ESCP revision.The British journal of surgery · 2024Guideline
- Guideline
- Trial
- Article
- Proximal bowel obstruction caused by high-grade duodenal adenocarcinoma: A rare case.Annals of medicine and surgery (2012) · 2025Article
- Advancements in endoscopic management of small-bowel polyps in Peutz-Jeghers syndrome and familial adenomatous polyposis.Therapeutic advances in gastroenterology · 2024Review
- Personalized endoscopic surveillance and intervention protocols for patients with familial adenomatous polyposis: the European FAP Consortium strategy.Endoscopy international open · 2023Article
- Role of endoscopy in patients with familial adenomatous polyposis.Frontline gastroenterology · 2022Article
- Endoscopic management of duodenal adenomatosis in familial adenomatous polyposis-A case-based review.United European gastroenterology journal · 2021Review
- Endocytoscopic observation with methylene blue staining for duodenal neoplasms associated with familial adenomatous polyposis.Scientific reports · 2020Article
- A Comprehensive Approach to the Management of Benign and Malignant Ampullary Lesions: Management in Hereditary and Sporadic Settings.Current gastroenterology reports · 2020Review
- Endoscopic ultrasound in the assessment of advanced duodenal adenomatosis in familial adenomatous polyposis.BMJ open gastroenterology · 2019Article
- Risk factors for advanced duodenal and ampullary adenomatosis in familial adenomatous polyposis: a prospective, single-center study.Endoscopy international open · 2018Article
- Hereditary Colorectal Polyposis and Cancer Syndromes: A Primer on Diagnosis and Management.The American journal of gastroenterology · 2017Review
- Duodenal adenocarcinoma: Advances in diagnosis and surgical management.World journal of gastrointestinal surgery · 2016Review
- Duodenal adenoma surveillance in patients with familial adenomatous polyposis.World journal of gastrointestinal endoscopy · 2015Review
- Prospective study of acute complication rates and associated risk factors in endoscopic therapy for duodenal adenomas.Surgical endoscopy · 2015Article
- Rare combination of familial adenomatous polyposis and gallbladder polyps.World journal of gastroenterology · 2014Article
- Endoscopic resection of ampullary lesions: a single-center 8-year retrospective cohort study of 91 patients with long-term follow-up.Surgical endoscopy · 2013Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundDuodenal lesions (DLS) are common in patients with familial adenomatosis polyposis (FAP), and screening for duodenal adenocarcinoma (DA) is currently recommended. Endoscopic treatment of DLS is controversial.
aimTo report management and outcomes of endoscopic therapy for DLS in patients with FAP.
methodsThe records of patients with FAP who underwent endoscopic surveillance or therapy for DLS over a 15-year period were reviewed. Endoscopic intervention included endoscopic surveillance with biopsies, argon plasma coagulation (APC), endoscopic mucosal resection (EMR), EMR with APC, and ampullectomy. Main outcome measurements were recurrence and histology of DLS after endoscopic therapy, complications of endoscopic therapy, and need for duodenectomy.
resultsSeventy-one patients with FAP and DLS were identified from our endoscopy database as undergoing upper endoscopy for screening and/or surveillance (1995-2009). Mean follow up was 4.5 years (1-15 years). Seventy of the seventy-one (98.5%) patients had multiple flat DLS. Most of the patients were followed with yearly biopsies. APC was performed in 17 patients and EMR was performed in eight patients; in five of the eight EMR patients, APC was also performed to treat the edges of EMR site. During the follow up, 17/55 (31%) patients had histological progression (HP). HP was seen in 5/16 (31%) patients who underwent APC (one was lost to follow-up) and 12/40 (30%) patients followed with biopsies alone. Recurrence of lesions was noted in all patients. Two patients underwent duodenectomy. None of the patients developed DA during follow up.
conclusionsEndoscopic surveillance with directed endotherapy for DLS in FAP is feasible and safe when diligently performed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.