Evidence map›Paper›PMID 21960063›Full record

SynthesisCurrent neurology and neuroscience reports2011

Intensity of aphasia therapy: evidence and efficacy.

Leora R Cherney, Janet P Patterson, Anastasia M Raymer

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Current neurology and neuroscience reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Rehabilitation interventions for Wernicke's aphasia and related fluent aphasia: A systematic review of randomized controlled trials.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Pooled it
  2. Trial
  3. Diagnosing and managing post-stroke aphasia.Expert review of neurotherapeutics · 2021
    Trial
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Neuroscience of aphasia recovery: the concept of neural multifunctionality.Current neurology and neuroscience reports · 2015
    Review
  17. Aphasia treatment: intensity, dose parameters, and script training.International journal of speech-language pathology · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Leora R CherneyCenter for Aphasia Research and Treatment, Rehabilitation Institute of Chicago, 345 East Superior Street, Chicago, IL 60611, USA, Lcherney@ric.org
Janet P Patterson
Anastasia M Raymer

Funding

Transcranial Direct Current Stimulation and Aphasia Language TherapyR21DC009876 · NIDCD · REHABILITATION INSTITUTE OF CHICAGO D/B/A SHIRLEY RYAN ABILITYLAB · PI CHERNEY, LEORA R · 2009 to 2010
$426k
Communication Outcomes for Naming Treatments in AphasiaR15DC009690 · NIDCD · OLD DOMINION UNIVERSITY · PI RAYMER, ANASTASIA MARIE · 2008 to 2009
$257k
NIDCD NIH HHS R15DC009690NIDCD NIH HHS R21DC9876
6 · The paper itself

Abstract

Determining the optimal amount and intensity of treatment is essential to the design and implementation of any treatment program for aphasia. A growing body of evidence, both behavioral and biological, suggests that intensive therapy positively impacts outcomes. We update a systematic review of treatment studies that directly compares conditions of higher and lower intensity treatment for aphasia. We identify five studies published since 2006, review them for methodologic quality, and synthesize their findings with previous ones. For both acute and chronic aphasia, results at the language impairment and communication activity/participation levels tend to be more equivocal than previously demonstrated, with no clear differences between intensive and nonintensive treatment emerging across studies. Future research directions are discussed including research design, definitions of treatment intensity, and behavioral and biological measurement of short- and long-term changes following implementation of an intensive treatment.

Indexed as

AphasiaBehaviorClinical Trials as TopicCommunicationHumansLearningNervous System DiseasesQuality of Health CareRandomized Controlled Trials as TopicTreatment Outcome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.